Evidence map›Paper›PMID 25589061›Full record

ArticleScientific reports2015

Within-visit blood pressure variability is associated with prediabetes and diabetes.

Rieko Okada, Yoshinari Yasuda, Kazuyo Tsushita, Kenji Wakai, Nobuyuki Hamajima, Seiichi Matsuo

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 32 citations in OpenAlex.

  1. Observational
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Visit-to-visit blood pressure variability and sleep architecture.Journal of clinical hypertension (Greenwich, Conn.) · 2021
    Article
  9. Article
  10. Prevalence and predictors of prediabetes and its coexistence with high blood pressure in first-degree relatives of patients with type 2 diabetes: A 9-year cohort study.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2020
    Article
  11. Implications of blood pressure variations in older populations.Hypertension research : official journal of the Japanese Society of Hypertension · 2019
    Review
  12. Article
  13. Article
  14. Arterial pressure lability is improved by sodium-glucose cotransporter 2 inhibitor in streptozotocin-induced diabetic rats.Hypertension research : official journal of the Japanese Society of Hypertension · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Rieko OkadaDepartment of Preventive Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Yoshinari YasudaDepartment of Nephrology, Internal Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Kazuyo TsushitaComprehensive Health Science Center, Aichi Health Promotion Foundation, Aichi, Japan.
Kenji WakaiDepartment of Preventive Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Nobuyuki HamajimaDepartment of Young Leaders' Program in Health Care Administration, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Seiichi MatsuoDepartment of Nephrology, Internal Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Nagoya University · JPAichi Health Promotion Foundation · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We investigated the associations between within-visit blood pressure variability (BPV) and risk factors for cardiovascular disease (CVD). The study subjects included 17,795 people aged 40-74 years who underwent health check-ups in Aichi Prefecture, Japan, and completed two blood pressure measurements. Subjects were categorized into three groups according to the difference of systolic blood pressure (ΔSBP), namely, low-BPV (≤ 10 mmHg), moderate-BPV (11-20 mmHg), and high-BPV (> 20 mmHg). Subjects were also divided into three categories as those without prediabetes (glycosylated hemoglobin A1c [HbA1c] < 5.7%), prediabetes (HbA1c 5.7-6.4%) and diabetes (HbA1c ≥ 6.5% or under treatment for diabetes). The proportion of prediabetes and diabetes were significantly higher in subjects with high-BPV than in those with low-BPV after adjusting for age, sex, and mean SBP (odds ratio [95% confidence interval] was 1.16 [1.01-1.33] for prediabetes and 1.33 [1.06-1.66] for diabetes). Other CVD risk factors were not associated with high-BPV after the adjustment. In conclusion, increased within-visit BPV was significantly associated with the prevalence of prediabetes and diabetes, independent of mean SBP, in a large general population. Therefore, assessing BPV in a single visit may help to identify subjects at increased risk of impaired glycemic control.

Indexed as

AdultAgedBlood PressureCardiovascular DiseasesDiabetes Mellitus, Type 2FemaleGlycated HemoglobinHumansMaleMiddle AgedOdds RatioPrediabetic StatePrevalenceRisk FactorsGlycated Hemoglobinhemoglobin A1c protein, human

Identifiers

PMID25589061
PMCPMC4295087
OpenAlexW2025126461

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.