Evidence map›Paper›PMID 25588408›Full record

Trial reportAmerican journal of Alzheimer's disease and other dementias2015

The effectiveness of reality orientation in the treatment of Alzheimer's disease.

Carlos Henrique Ferreira Camargo, Filipe Fernandes Justus, Giuliano Retzlaff

Open access · greenAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in American journal of Alzheimer's disease and other dementias, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 5 pooled it
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 5 syntheses or guidelines pooled it, 43 citations in OpenAlex.

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  16. The Effectiveness of Reality Orientation Therapy in the Treatment of Parkinson Disease Dementia.American journal of Alzheimer's disease and other dementias · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Carlos Henrique Ferreira CamargoDepartment of Medicine, Hospital Universitário, State University of Ponta Grossa, Ponta Grossa, Paraná, Brazil chcamargo@uol.com.br.
Filipe Fernandes JustusDepartment of Medicine, Hospital Universitário, State University of Ponta Grossa, Ponta Grossa, Paraná, Brazil.
Giuliano RetzlaffDepartment of Medicine, Hospital Universitário, State University of Ponta Grossa, Ponta Grossa, Paraná, Brazil.
Universidade Estadual de Ponta Grossa · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alzheimer's disease (AD) is the most frequent cause of dementia. This work aims to assess the effectiveness of reality orientation (RO), a traditional, extensively documented cognitive enhancement technique, when combined with acetylcholinesterase inhibitors in the treatment of AD. Fourteen patients with AD having mild to moderate dementia receiving standard treatment with donepezil were randomly assigned to control and treatment groups. Patients in the treatment group were submitted to weekly RO sessions for 6 months. Cognitive outcomes were assessed based on scores in the Consortium to Establish a Registry for Alzheimer's Disease (CERAD) neuropsychological battery and the Clock Drawing Test (CDT). Mean CERAD neuropsychological battery, Mini-Mental State Examination (MMSE), and CDT scores improved in the treatment group and worsened in the control group. A number of CERAD neuropsychological battery and MMSE scores were statistically significant. Our findings suggest that RO is a valuable long-term complementary intervention for dementia in AD.

Indexed as

OrientationAgedAged, 80 and overAlzheimer DiseaseCholinesterase InhibitorsCombined Modality TherapyDonepezilFemaleHumansIndansMaleNeurological RehabilitationNeuropsychological TestsPiperidinesSeverity of Illness IndexTreatment OutcomeCholinesterase InhibitorsDonepezilIndansPiperidinesAlzheimer’s diseasecognitiondementiareality orientation

Identifiers

PMID25588408
PMCPMC10852646
OpenAlexW2163931952

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.