Evidence map›Paper›PMID 25588123›Full record

ArticleJAMA psychiatry2015

Changes in drug coverage generosity and untreated serious mental illness: transitioning from Medicaid to Medicare Part D.

Jeanne M Madden, Alyce S Adams, Robert F LeCates, Dennis Ross-Degnan, Fang Zhang, Haiden A Huskamp, Daniel M Gilden, Stephen B Soumerai

Open access · greenAbstract read
In one paragraph

Article in JAMA psychiatry, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 14 citations in OpenAlex.

  1. Pharmaceutical policies: effects of regulating drug insurance schemes.The Cochrane database of systematic reviews · 2022
    Pooled it
  2. Pooled it
  3. Article
  4. Generosity of state insurance mandates and growth in the workforce for autism spectrum disorder.Autism : the international journal of research and practice · 2021
    Article
  5. Article
  6. Effects of Transitioning to Medicare Part D on Access to Drugs for Medical Conditions among Dual Enrollees with Cancer.Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research · 2017
    Article
  7. Missing clinical and behavioral health data in a large electronic health record (EHR) system.Journal of the American Medical Informatics Association : JAMIA · 2016
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Jeanne M MaddenDepartment of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, Massachusetts.
Alyce S AdamsDivision of Research, Kaiser Permanente, Oakland, California.
Robert F LeCatesDepartment of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, Massachusetts.
Dennis Ross-DegnanDepartment of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, Massachusetts.
Fang ZhangDepartment of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, Massachusetts.
Haiden A HuskampDepartment of Health Care Policy, Harvard Medical School, Boston, Massachusetts.
Daniel M GildenJEN Associates, Inc, Cambridge, Massachusetts.
Stephen B SoumeraiDepartment of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, Massachusetts.
Harvard University · USHarvard Pilgrim Health Care · USAbt Global (United States) · USKaiser Permanente · US

Funding

SSRI's and SuicidalityU19MH092201 · NIMH · KAISER FOUNDATION RESEARCH INSTITUTE · PI SIMON, GREGORY E. · 2010 to 2018
$19.5M
Translational Research Core - Health Engagement & Action Translational (HEAT)P30DK092924 · NIDDK · KAISER FOUNDATION RESEARCH INSTITUTE · PI Alyce Sophia Adams, HILARY Kessler SELIGMAN · 2011 to 2026
$9.2M
Impact of Medicare Drug Benefit on Use and Cost-related Underuse of MedicinesR01AG028745 · NIA · HARVARD PILGRIM HEALTH CARE, INC. · PI SOUMERAI, STEPHEN B · 2006 to 2014
$3.2M
Drug Cost Containment Changes and Quality of Care for Mentally Ill Dual EnrolleesR01HS018577 · AHRQ · HARVARD PILGRIM HEALTH CARE, INC. · PI SOUMERAI, STEPHEN B · 2009 to 2012
$1.9M
Impact of Medicare Part D on Cancer and Diabetes Disparities among Dual EnrolleesR01AG032249 · NIA · KAISER FOUNDATION RESEARCH INSTITUTE · PI ADAMS, ALYCE SOPHIA · 2009 to 2011
$1.5M
AHRQ HHS R01 HS018577NIA NIH HHS 5R01AG028745NIA NIH HHS 5R01AG032249NIA NIH HHS R01 AG028745NIA NIH HHS R01 AG032249NIDDK NIH HHS 1P30-DK092924NIDDK NIH HHS P30 DK092924NIMH NIH HHS U19 MH092201NIMH NIH HHS U19MH092201
6 · The paper itself

Abstract

importanceMore than 1 in 5 disabled people with dual Medicare-Medicaid enrollment have schizophrenia or a bipolar disorder (ie, a serious mental illness). The effect of their transition from Medicaid drug coverage, which varies in generosity across states, to the Medicare Part D drug benefit is unknown. Many thousands make this transition annually.

objectivesTo determine the effect of transitioning from Medicaid drug benefits to Medicare Part D on medication use by patients with a serious mental illness and to determine the influence of Medicaid drug caps. DESIGN, SETTING, AND

participantsIn time-series analysis of continuously enrolled patient cohorts (2004-2007), we estimated changes in medication use before and after transitioning to Part D, comparing states that capped monthly prescription fills with states with no prescription limits. We used Medicaid and Medicare claims from a 5% national sample of community-dwelling, nonelderly disabled dual enrollees with schizophrenia (n = 5554) or bipolar disorder (n = 3675). MAIN OUTCOMES AND MEASURES: Psychotropic treatments included antipsychotics for schizophrenia and antipsychotics, anticonvulsants, and lithium for bipolar disorder. We measured monthly rates of untreated illness, intensity of treatment, and overall prescription medication use.

resultsPrior to Part D, the prevalence of untreated illness among patients with a bipolar disorder was 30.0% in strict-cap states and 23.8% in no-cap states. In strict-cap states, the proportion of untreated patients decreased by 17.2% (relatively) 1 year after Part D, whereas there was no change in the proportion of untreated patients in no-cap states. For patients with schizophrenia, the untreated rate (20.6%) did not change in strict-cap states, yet it increased by 23.3% (from 11.6%) in no-cap states. Overall medication use increased substantially after Part D in strict-cap states: prescription fills were 35.5% higher among patients with a bipolar disorder and 17.7% higher than predicted among schizophrenic patients; overall use in no-cap states was unchanged in both cohorts. CONCLUSIONS AND RELEVANCE: The effects of transitioning from Medicaid to Medicare Part D on essential treatment of serious mental illness vary by state. Transition to Part D in states with strict drug benefit limits may reduce rates of untreated illness among patients with bipolar disorders, who have high levels of overall medication use. Access to antipsychotic treatment may decrease after Part D for patients with a serious mental illness living in states with relatively generous uncapped Medicaid coverage.

Indexed as

AdultBipolar DisorderDrug PrescriptionsFemaleHumansMaleMedicaidMedicare Part DMiddle AgedPrevalencePsychotropic DrugsSchizophreniaUnited StatesYoung AdultPsychotropic Drugs

Identifiers

PMID25588123
PMCPMC4505620
OpenAlexW2058417208

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.