ArticleACS nano2015
Optical drug monitoring: photoacoustic imaging of nanosensors to monitor therapeutic lithium in vivo.
Article in ACS nano, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
53 citing papers in PubMed.
- A fluorous-phase oxygen optical nanosensor for mitigating redox-active microbial metabolite interference.The Analyst · 2026Article
- Perspective on Ionophore-Based Ion-Selective Nanosensors for pH-Independent Quantitative Lysosomal Calcium Imaging.Chemical & biomedical imaging · 2026Review
- Mass transfer in heterogeneous biofilms: Key issues in biofilm reactors and AI-driven performance prediction.Environmental science and ecotechnology · 2024Review
- Shedding light on ultrasound in action: Optical and optoacoustic monitoring of ultrasound brain interventions.Advanced drug delivery reviews · 2024Review
- Article
- Photoacoustic Chemical Imaging Sodium Nano-Sensor Utilizing a Solvatochromic Dye Transducer for In Vivo Application.Biosensors · 2023Article
- DNA-AgNC Loaded Liposomes for Measuring Cerebral Blood Flow Using Two-Photon Fluorescence Correlation Spectroscopy.ACS nano · 2023Article
- Activity-Based Photoacoustic Probes for Detection of Disease Biomarkers beyond Oncology.ACS bio & med chem Au · 2023Review
- The sound of blood: photoacoustic imaging in blood analysis.Medicine in novel technology and devices · 2023Article
- Supramolecular Loading of DNA Hydrogels with Dye-Drug Conjugates for Real-Time Photoacoustic Monitoring of Chemotherapy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022Article
- Real-Time,ACS sensors · 2022Review
- Dual-wavelength photoacoustic atlas method to estimate fractional methylene blue and hemoglobin contents.Journal of biomedical optics · 2022Article
- Recent advances in aggregation-induced emission luminogens in photoacoustic imaging.European journal of nuclear medicine and molecular imaging · 2022Review
- Perspective on fluorescence cell imaging with ionophore-based ion-selective nano-optodes.Biomicrofluidics · 2022Article
- Targeted contrast agents and activatable probes for photoacoustic imaging of cancer.Chemical Society reviews · 2022Review
- Advances in Therapeutic Monitoring of Lithium in the Management of Bipolar Disorder.Sensors (Basel, Switzerland) · 2022Review
- Wavelength and pulse energy optimization for detecting hypoxia in photoacoustic imaging of the neonatal brain: a simulation study.Biomedical optics express · 2021Article
- Acoustics at the nanoscale (nanoacoustics): A comprehensive literature review.: Part II: Nanoacoustics for biomedical imaging and therapy.Sensors and actuators. A, Physical · 2021Article
- Photoacoustics for listening to metal nanoparticle super-aggregates.Nanoscale advances · 2021Article
- LipiSensors: Exploiting Lipid Nanoemulsions to Fabricate Ionophore-Based Nanosensors.Biosensors · 2020Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Personalized medicine could revolutionize how primary care physicians treat chronic disease and how researchers study fundamental biological questions. To realize this goal, we need to develop more robust, modular tools and imaging approaches for in vivo monitoring of analytes. In this report, we demonstrate that synthetic nanosensors can measure physiologic parameters with photoacoustic contrast, and we apply that platform to continuously track lithium levels in vivo. Photoacoustic imaging achieves imaging depths that are unattainable with fluorescence or multiphoton microscopy. We validated the photoacoustic results that illustrate the superior imaging depth and quality of photoacoustic imaging with optical measurements. This powerful combination of techniques will unlock the ability to measure analyte changes in deep tissue and will open up photoacoustic imaging as a diagnostic tool for continuous physiological tracking of a wide range of analytes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.