ArticleThe New England journal of medicine2015
Coronary heart disease and genetic variants with low phospholipase A2 activity.
Article in The New England journal of medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Genetic invalidation of Lp-PLAEuropean journal of preventive cardiology · 2017Pooled it
- Lp-PLA2, scavenger receptor class B type I gene (SCARB1) rs10846744 variant, and cardiovascular disease.PloS one · 2018Trial
- Pharmacogenomics-based systematic review of coronary artery disease based on personalized medicine procedure.Heliyon · 2024Article
- Pathogenesis of premature coronary artery disease: Focus on risk factors and genetic variants.Genes & diseases · 2022Review
- Sleep Disordered Breathing, Obesity and Atrial Fibrillation: A Mendelian Randomisation Study.Genes · 2022Article
- On the present and future role of Lp-PLAArchives of medical science : AMS · 2021Article
- Lipoprotein-associated phospholipase A2: The story continues.Medicinal research reviews · 2020Review
- Mendelian Randomization Studies Promise to Shorten the Journey to FDA Approval.JACC. Basic to translational science · 2018Article
- Lipoprotein-associated phospholipase AAtherosclerosis · 2018Article
- Mendelian randomization in cardiometabolic disease: challenges in evaluating causality.Nature reviews. Cardiology · 2017Review
- Leveraging human genetics to guide drug target discovery.Trends in cardiovascular medicine · 2017Review
- Genetics of coronary artery disease: discovery, biology and clinical translation.Nature reviews. Genetics · 2017Review
- Article
- Recent Developments in Mendelian Randomization Studies.Current epidemiology reports · 2017Review
- Using Mendelian Randomization studies to Assess Causality and Identify New Therapeutic Targets in Cardiovascular Medicine.Current genetic medicine reports · 2016Article
- Genetics-Current and Future Role in the Prevention and Management of Coronary Artery Disease.Current atherosclerosis reports · 2016Review
- A phenome-wide association study of a lipoprotein-associated phospholipase A2 loss-of-function variant in 90 000 Chinese adults.International journal of epidemiology · 2016Article
- A Causal Network Analysis of the Fatty Acid Metabolome in African-Americans Reveals a Critical Role for Palmitoleate and Margarate.Omics : a journal of integrative biology · 2016Article
- Surprises From Genetic Analyses of Lipid Risk Factors for Atherosclerosis.Circulation research · 2016Review
- Lipoprotein associated phospholipase A2 activity, apolipoprotein C3 loss-of-function variants and cardiovascular disease: The Atherosclerosis Risk In Communities Study.Atherosclerosis · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
PubMed holds no abstract for this paper.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.