Evidence map›Paper›PMID 25587425›Full record

ArticleBiosensors2014

Microelectrode Arrays and the Use of PEG-Functionalized Diblock Copolymer Coatings.

Sakshi Uppal, Matthew D Graaf, Kevin D Moeller

Open access · goldAbstract read
In one paragraph

Article in Biosensors, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Sakshi UppalDepartment of Chemistry, Washington University in St. Louis, St. Louis, MO 63130, USA; E-Mails: suppal@wustl.edu (S.U.); mgraaf@wustl.edu (M.D.G.).
Matthew D GraafDepartment of Chemistry, Washington University in St. Louis, St. Louis, MO 63130, USA; E-Mails: suppal@wustl.edu (S.U.); mgraaf@wustl.edu (M.D.G.).
Kevin D MoellerDepartment of Chemistry, Washington University in St. Louis, St. Louis, MO 63130, USA; E-Mails: suppal@wustl.edu (S.U.); mgraaf@wustl.edu (M.D.G.).
Washington University in St. Louis · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PEG-modified diblock copolymer surfaces have been examined for their compatibility with microelectrode array based analytical methods. The use of PEG-modified polymer surfaces on the arrays was initially problematic because the redox couples used in the experiments were adsorbed by the polymer. This led the current measured by cyclic voltammetry for the redox couple to be unstable and increase with time. However, two key findings allow the experiments to be successful. First, after multiple cyclic voltammograms the current associated with the redox couple does stabilize so that a good baseline current can be established. Second, the rate at which the current stabilizes is consistent every time a particular coated array is used. Hence, multiple analytical experiments can be conducted on an array coated with a PEG-modified diblock copolymer and the data obtained is comparable as long as the data for each experiment is collected at a consistent time point.

Indexed as

cyclic voltammetryferrocene carboxylic acidmicroelectrode arraysPEG

Identifiers

PMID25587425
PMCPMC4264361
OpenAlexW1975230575

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.