ReviewGMS current topics in otorhinolaryngology, head and neck surgery2014
Diseases of the nose and paranasal sinuses in child.
Review in GMS current topics in otorhinolaryngology, head and neck surgery, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- Content Validity of Patient-Reported Outcome Measures Developed for Assessing Disease-Specific Quality of Life in Children With Sinonasal Disease: A Systematic Review.International forum of allergy & rhinology · 2025Pooled it
- Biomechanical and Aerodynamic Modulation for Sinonasal Homeostasis in Craniofacial Orthopedics: A Comprehensive Review of RAMPA Therapy.Biomimetics (Basel, Switzerland) · 2026Review
- CraniofacialMorphometric Associations with Frontal Sinus Hypoplasia/Aplasia in Adults: Orbital and Upper Facial Differences on CT.Diagnostics (Basel, Switzerland) · 2026Article
- Mechanotherapeutic Modulation of the Nasal Microenvironment: RAMPA-Induced Maxillofacial Remodeling and Its Pathophysiological Impact on Mucus Rheology and Chronic Inflammation.Bioengineering (Basel, Switzerland) · 2026Article
- CBCT Volumetric Changes in Combined Nasal Cavity and Paranasal Sinuses Following RAMPA-ROA Therapy: A Retrospective Cohort Study with Reference to Longitudinal Growth Data.Journal of clinical medicine · 2026Article
- Investigating the Morphology of the Nasal Cavity for Nasal Reconstruction Using Cone Beam Computed Tomography Images : Morphology of the Nasal Cavity for Nasal Reconstruction.Galen medical journal · 2024Article
- Paranasal sinus development and implications for imaging.Pediatric radiology · 2021Review
- Automatic forensic identification using 3D sphenoid sinus segmentation and deep characterization.Medical & biological engineering & computing · 2020Article
- Analysis of the development of human foetal nasal turbinates using CBCT imaging.Surgical and radiologic anatomy : SRA · 2019Article
- Characterisation of antibiotic prescriptions for acute respiratory tract infections in Danish general practice: a retrospective registry based cohort study.NPJ primary care respiratory medicine · 2017Article
- Paediatric Virology: A rapidly increasing educational challenge.Experimental and therapeutic medicine · 2017Article
- Translation and Validation of the Sinus and Nasal Quality of Life Surgery Survey in Serbian.OTO openArticle
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Diseases of the pediatric nose and nasal sinuses as well as neighboring anatomical structures encompass a variety of pathologies, especially of inflammatory nature. Congenital disease, such as malformations and structural deviations of the nasal septum, as well as systemic metabolic pathologies affecting the nose and sinuses, rarely require medical therapy from an Otolaryngologist. The immunological function of the mucosa and genetic factors play a role in the development of disease in the pediatric upper airway tract, especially due to the constantly changing anatomy in this growth phase. Disease description of the nose and nasal sinuses due to mid-facial growth must also take developmental age differences (infant, toddler, preschool, and school age) into account. Epidemiological examinations and evidence based studies are often lacking in the pediatric population. The wide range of inflammatory diseases of the nose and paranasal sinuses, such as the acute and chronic rhinosinusitis, the allergic rhinitis, and adenoid disease, play a role in the susceptibility of a child to infection. The susceptibility to infection depends on the pediatric age structure (infant, young child) and has yet to be well defined. The acute rhinosinusitis in children develops after a viral infection of the upper airways, also referred to as the "common cold" in the literature. It usually spontaneously heals within ten days without any medical therapy. Antibiotic therapy is prudent in complicated episodes of ARS. The antibiotic therapy is reserved for children with complications or associated disease, such as bronchial asthma and/or chronic bronchitis. A chronic rhinosinusitis is defined as the inflammatory change in the nasal mucosa and nasal sinus mucosa, in which the corresponding symptoms persist for over 12 weeks. The indication for CT-imaging of the nasal sinuses is reserved for cases of chronic rhinosinusitis that have been successfully treated with medication. A staged therapeutic concept is followed in CRS based on conservative and surgical methods. Nasal sinus surgery is considered nowadays as effective and safe in children. Based on the assumption that adenoids are a reservoir for bacteria, from which recurrent infections of the nose and nasal sinus originate, the adenoidectomy is still defined as a cleansing procedure in rhinosinusitis. 69.3% of the children had benefit from adenoidectomy. Comorbidities, such as pediatric bronchial asthma, presently play an even more important role in the therapy of rhinosinusitis; therefore, it is often wise to have the support of pediatricians. In western European countries 40% of children presently suffer from allergic rhinitis, in which pronounced nasal obstruction can cause disturbed growth in facial bones. An early therapy with SIT may prevent the development of bronchial asthma and secondary sensitization to other allergens. Therefore, SIT is recommended in treatment of allergic rhinitis whenever, if possible. The assessment of diagnostic tools is for the examiner not often possible due to the lack of evidence. Rhinosurgical approaches are often described in study reports; however, they lack the standard prospective randomized long-term study design required nowadays and can only be evaluated with caution in the literature.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.