Evidence map›Paper›PMID 25586914›Full record

ArticleJournal of interpersonal violence2016

Prospective Study of the Mental Health Consequences of Sexual Violence Among Women Living With HIV in Rural Uganda.

Alexander C Tsai, William R Wolfe, Elias Kumbakumba, Annet Kawuma, Peter W Hunt, Jeffrey N Martin, David R Bangsberg, Sheri D Weiser

Abstract read
In one paragraph

Article in Journal of interpersonal violence, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  18. PMTCT Adherence in Pregnant South African Women: The Role of Depression, Social Support, Stigma, and Structural Barriers to Care.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Alexander C TsaiMassachusetts General Hospital, Boston, MA, USA Mbarara University of Science and Technology, Uganda Harvard Medical School, Boston, MA, USA actsai@partners.org.
William R WolfeUniversity of California at San Francisco, CA, USA.
Elias KumbakumbaMbarara University of Science and Technology, Uganda.
Annet KawumaMbarara University of Science and Technology, Uganda.
Peter W HuntUniversity of California at San Francisco, CA, USA.
Jeffrey N MartinUniversity of California at San Francisco, CA, USA.
David R BangsbergMassachusetts General Hospital, Boston, MA, USA Mbarara University of Science and Technology, Uganda Harvard Medical School, Boston, MA, USA Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Sheri D WeiserUniversity of California at San Francisco, CA, USA.

Funding

Virology CoreP30AI027763 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI STEVEN Grant DEEKS · 1988 to 2026
$93.6M
Ujima Mentoring ProgramP30MH062246 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Sheri Ann Lippman · 2001 to 2026
$57.4M
TB PREVENTION AND HIV IN THE HOMELESS--AN INTERVENTIONR01MH054907 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BANGSBERG, DAVID ROY · 1995 to 2014
$20.7M
Microenterprise to empower and improve health of HIV+ women in UgandaK23MH096620 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI TSAI, ALEXANDER C · 2012 to 2016
$922k
The Impact of Food Insecurity on HIV Outcomes and Sexual Risk Behavior in UgandaK23MH079713 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI WEISER, SHERI DAWN · 2007 to 2011
$921k
Mentoring Patient Oriented Adherence Research in UgandaK24MH087227 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI BANGSBERG, DAVID ROY · 2009 to 2013
$776k
NIAID NIH HHS P30 AI027763NIMH NIH HHS K23 MH079713NIMH NIH HHS K23MH079713NIMH NIH HHS K23 MH096620NIMH NIH HHS K23MH096620NIMH NIH HHS K24 MH087227NIMH NIH HHS K24MH087227NIMH NIH HHS P30 MH062246NIMH NIH HHS R01 MH054907NIMH NIH HHS R01MH054907PHS HHS P30A1027763
6 · The paper itself

Abstract

The association between sexual violence and depression is well known, but the temporal aspects of the association have not been well established. We analyzed data from a cohort of 173 HIV-positive women in rural Uganda who were interviewed every 3 months for a median of 1.8 years of follow-up. The method of generalized estimating equations (GEE) was used to model the marginal expectation of depression symptom severity (Hopkins Symptom Checklist for Depression), mental health-related quality of life (MOS-HIV Mental Health Summary), and heavy drinking (Alcohol Use Disorders Identification Test) as a function of self-reported forced-sex victimization in the 3 months prior to interview. Estimates were adjusted for variables known to confound the association between victimization and mental health status. To assess any potential reciprocal relationships, we reversed the temporal ordering of the exposures and outcomes and refitted similar GEE models. In multivariable analyses, victimization was associated with greater depression symptom severity (b = 0.17; 95% CI = [0.02, 0.33]) and lower mental health-related quality of life (b = -5.65; 95% CI = [-9.34, -1.96]), as well as increased risks for probable depression (adjusted relative risk [ARR] = 1.58; 95% CI = [1.01, 2.49) and heavy drinking (ARR = 3.99; 95% CI = [1.84, 8.63]). We did not find strong evidence of a reciprocal relationship. Our findings suggest that forced sex is associated with adverse mental health outcomes among HIV-positive women in rural Uganda. Given the substantial mental health-related impacts of victimization, effective health sector responses are needed.

Indexed as

AdultCrime VictimsDepressive DisorderFemaleHealth StatusHIV InfectionsHumansMental HealthMental Status ScheduleProspective StudiesRapeRural PopulationSelf ReportUgandadepressive disorderdomestic violenceHIVrapeUganda

Identifiers

PMID25586914
PMCPMC4500676

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.