Evidence map›Paper›PMID 25585996›Full record

ArticleAmerican journal of Alzheimer's disease and other dementias2015

ApoE type 4 allele affects cognitive function of aged population in Tianjin City, China.

Shoudan Sun, Jingming Fu, Jun Chen, Wei Pang, Ruomei Hu, Haiqiang Li, Long Tan, Yugang Jiang

Open access · greenAbstract read
In one paragraph

Article in American journal of Alzheimer's disease and other dementias, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Associations of Vascular Risk Factors,Frontiers in psychiatry · 2021
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Shoudan SunDepartment of Nutrition, Tianjin Institute of Health & Environmental Medicine, Tianjin, China Department of Nutrition, Tianjin Hospital, Tianjin, China.
Jingming FuDepartment of Nutrition, Tianjin Institute of Health & Environmental Medicine, Tianjin, China.
Jun ChenCollege of Acupuncture and tuina, Shandong University of Traditional Chinese Medicine, Jinan, China.
Wei PangDepartment of Nutrition, Tianjin Institute of Health & Environmental Medicine, Tianjin, China.
Ruomei HuDepartment of Nutrition, Tianjin Hospital, Tianjin, China.
Haiqiang LiDepartment of Nutrition, Tianjin Institute of Health & Environmental Medicine, Tianjin, China.
Long TanDepartment of Nutrition, Tianjin Institute of Health & Environmental Medicine, Tianjin, China.
Yugang JiangDepartment of Nutrition, Tianjin Institute of Health & Environmental Medicine, Tianjin, China jyg1967@126.com.
Tianjin Hospital · CNShandong University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Apolipoprotein E type 4 allele (ApoE∊4) is known as a risk gene for the late-onset Alzheimer's disease, and the relationship between ApoE∊4 and cognitive function of the elderly people has drawn the attention of the scientists. In this study, we investigated the relationship between ApoE∊4 and the cognitive function of the old people. A total of 156 old people were investigated, of whom 31 were ApoE∊4 carriers. The ApoE∊4 primarily influenced the global cognitive function, perceptual speed, and work memory. The results indicate that ApoE∊4 has significant negative effect on the cognitive function of the elderly people who are 60 years and older.

Indexed as

CognitionAgedAged, 80 and overAllelesApolipoprotein E4Asian PeopleChinaCognition DisordersFemaleGenotypeHumansMaleMemory, Short-TermMental Status ScheduleMiddle AgedNeuropsychological TestsApolipoprotein E4apolipoprotein E type 4 allelebasic cognitive aptitude testscognitive functionelderly peopleMMSE

Identifiers

PMID25585996
PMCPMC10852675
OpenAlexW2033928577

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.