Trial reportEarly intervention in psychiatry2016
Development of a group and family-based cognitive behavioural therapy program for youth at risk for psychosis.
Trial report in Early intervention in psychiatry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 18 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Game-based Telehealth Therapeutic Intervention in First Onset Psychosis
Telehealth Adaptation of Group and Family-Based Cognitive Behavioral Therapy for Youth at Risk for Psychosis
Who cites it
18 citing papers in PubMed, 4 syntheses or guidelines pooled it, 41 citations in OpenAlex.
- Clinical outcomes in individuals at clinical high risk of psychosis who do not transition to psychosis: a meta-analysis.Epidemiology and psychiatric sciences · 2022Pooled it
- Psychosis-like experiences and resilience: A systematic and critical review of the literature.Psychological services · 2022Pooled it
- Attenuated psychotic symptom interventions in youth at risk of psychosis: A systematic review and meta-analysis.Early intervention in psychiatry · 2019Pooled it
- Negative Symptom Interventions in Youth at Risk of Psychosis: A Systematic Review and Network Meta-analysis.Schizophrenia bulletin · 2018Pooled it
- Assessing Usage and Usability of a Narrative-Based Psychoeducational Digital Intervention to Improve Medication Adherence Among Individuals With Schizophrenia in a Stable Phase: Mixed Methods Study.Journal of medical Internet research · 2026Trial
- Do Psychological Interventions Reduce Paranoia in Adolescents? A Systematic Review.Clinical child and family psychology review · 2026Review
- Measuring Social and Role Recovery: Barbara Cornblatt and Colleagues' Global Functioning Scales and Their Role in Psychosocial Interventions for Clinical High-Risk and Early Psychosis.Schizophrenia bulletin · 2026Article
- Navigating the Maze: Caregiver Perspectives on Pathways to Mental Health Care for U.S. Youth at Clinical High Risk for Psychosis.Early intervention in psychiatry · 2025Article
- Psychoeducation for individuals at clinical high risk for psychosis: A scoping review.Schizophrenia research · 2023Article
- A case report and first-person account of an individual at risk for psychosis who improved during the COVID-19 pandemic.Psychosis · 2022Article
- Cross-Sectional Descriptive Pilot Study on the Risk of Psychotic Disorders among Adolescents.Children (Basel, Switzerland) · 2021Article
- Predictors of internalized mental health stigma in a help-seeking sample of youth: The roles of psychosis-spectrum symptoms and family functioning.Journal of abnormal psychology · 2021Article
- Telepsychotherapy with Youth at Clinical High Risk for Psychosis: Clinical Issues and Best Practices during the COVID-19 Pandemic.Journal of psychotherapy integration · 2020Article
- The Global Functioning: Social and Role Scales-Further Validation in a Large Sample of Adolescents and Young Adults at Clinical High Risk for Psychosis.Schizophrenia bulletin · 2019Article
- Advances in clinical staging, early intervention, and the prevention of psychosis.F1000Research · 2019Review
- Potentially important periods of change in the development of social and role functioning in youth at clinical high risk for psychosis.Development and psychopathology · 2018Article
- Oxidative stress, prefrontal cortex hypomyelination and cognitive symptoms in schizophrenia.Translational psychiatry · 2017Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 7 institutions in 2 countries.
Funding
Abstract
objectiveThe onset of psychosis typically occurs during adolescence or early adulthood and can have a detrimental impact on social and cognitive development. Cognitive behavioural therapy (CBT) shows promise in reducing the risk of psychosis. Teaching families to apply CBT with their offspring may bolster therapeutic gains made in time-limited treatment. We developed a comprehensive group-and-family-based CBT (GF-CBT) program that aims to facilitate psychosocial recovery, decrease symptoms and prevent transition to psychosis in youth at risk. GF-CBT is grounded in ecological systems and cognitive theories, resilience models and research on information processing in delusions. The theoretical rationale and description of GF-CBT are presented together with a pilot study that evaluated the program's feasibility and explored participants' outcomes.
methodsYouth ages 16-21 at risk for psychosis and their families participated in an open trial with pre, post and 3-month follow-up assessments conducted by an independent evaluator. The Comprehensive Assessment of At-Risk Mental States was the primary clinical outcome measure.
resultsAll enrolled participants (n = 6) completed GF-CBT and all remitted from at-risk mental state (ARMS). As a group participants showed statistically significant decreases in attenuated psychotic symptoms, negative symptoms, depression, cognitive biases and improvements in functioning. Family members showed significant improvements in use of CBT skills, enhanced communication with their offspring, and greater confidence in their ability to help. Gains were maintained at follow-up.
conclusionsGF-CBT may delay or prevent transition to psychosis in youth at risk, and potentially facilitate recovery from ARMS. More rigorous, controlled research is needed to further evaluate this program.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.