Evidence map›Paper›PMID 25585605›Full record

ArticleParasitology research2015

In vivo anthelmintic activity of Carex baccans and its active principle resveratrol against Hymenolepis diminuta.

Bikash Ranjan Giri, Ravi Rao Bharti, Bishnupada Roy

Abstract read
PubMed Publisher
In one paragraph

Article in Parasitology research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.5field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Article
  3. Resveratrol againstTropical medicine and infectious disease · 2023
    Article
  4. The TapewormPathogens (Basel, Switzerland) · 2022
    Review
  5. Article
  6. Article
  7. Review
  8. International journal of veterinary science and medicine · 2018
    Article
  9. Genistein: is the multifarious botanical a natural anthelmintic too?Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2018
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Bikash Ranjan GiriParasitology Laboratory, Department of Zoology, North-Eastern Hill University, Shillong, Meghalaya, 793022, India.
Ravi Rao Bharti
Bishnupada Roy
North Eastern Hill University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anthelmintic resistance against most of the commercial drugs is a great threat to humans as well as the veterinary live stocks. Hence, new treatment strategies to control helminth infections are essential at this hour. Carex baccans Nees has been traditionally used by Jaintia tribes in Northeast India to get rid of intestinal worm infections. Therefore, the present study was conducted to evaluate in vivo cestocidal activity of root tuber extract of C. baccans and its active component resveratrol against the zoonotic cestode Hymenolepis diminuta in the experimental model rat. The cestocidal activity was determined by monitoring the eggs per gram (EPG) counts in faeces of different treated groups. The result showed that the highest dose of the plant extract (50 mg/kg) and resveratrol (4.564 mg/kg body weight) has significant anthelmintic efficacy against H. diminuta. Crude extract of the plant as well as resveratrol reduced EPG count (56.012 and 46.049 %) and also resulted in decreased worm burden by 44.287 and 31.034 %, respectively. The efficacy of the crude extract and resveratrol can be compared to the reference drug praziquantel. The results exhibits considerable cestocidal potential of root tuber crude extract of C. baccans and resveratrol and justify its folklore use.

Indexed as

Carex PlantPhytotherapyAnimalsAnticestodal AgentsDose-Response Relationship, DrugFemaleHymenolepiasisHymenolepis diminutaIndiaMaleParasite Egg CountPlant ExtractsPlant TubersPraziquantelRatsResveratrolAnticestodal AgentsPlant ExtractsPraziquantelResveratrolStilbenes

Identifiers

PMID25585605
OpenAlexW1989958786

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.