Evidence map›Paper›PMID 25584767›Full record

ReviewGynecologic oncology2015

Basic science and clinical management of painful and non-painful chemotherapy-related neuropathy.

Joyce H Kim, Patrick M Dougherty, Salahadin Abdi

Abstract readReview
In one paragraph

Review in Gynecologic oncology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Neuropathic Pain in Cancer: What Are the Current Guidelines?Current treatment options in oncology · 2024
    Review
  11. Article
  12. Article
  13. Chemotherapy-induced polyneuropathy in cancer care-the patient perspective.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Joyce H KimDepartment of Pain Medicine, The University of Texas, MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, United States.
Patrick M DoughertyDepartment of Pain Medicine, The University of Texas, MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, United States.
Salahadin AbdiDepartment of Pain Medicine, The University of Texas, MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, United States. Electronic address: sabdi@mdanderson.org.

Funding

Mechanisms of Chemotherapy-Induced Peripheral PainR01NS046606 · NINDS · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI DOUGHERTY, PATRICK M · 2007 to 2015
$3.3M
The role of ENF loss, TLR4 and spinal plasticity in paclitaxel CIPNR01CA200263 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI DOUGHERTY, PATRICK M · 2016 to 2020
$2.4M
NCI NIH HHS R01 CA200263NINDS NIH HHS R01 NS046606
6 · The paper itself

Abstract

Chemotherapy-induced peripheral neuropathy (CIPN) is a dose-limiting toxicity of several chemotherapeutics used in the treatment of all the most common malignancies. There are several defined mechanisms of nerve damage that take place along different areas of the peripheral and the central nervous system. Treatment is based on symptom management and there are several classes of medications found to be efficacious in the treatment of neuropathic pain. Neuropathic pain that persists despite appropriate pharmacotherapy may respond to interventional procedures that span a range of invasiveness. The purpose of this review article is to examine the basic science of neuropathy and currently available treatment options in the context of chemotherapy induced peripheral neuropathy.

Indexed as

Analgesics, OpioidAnesthetics, LocalAnticonvulsantsAntidepressive AgentsAntineoplastic AgentsHumansNeoplasmsNeuralgiaOccupational TherapyPainPeripheral Nervous System DiseasesPhysical Therapy ModalitiesTranscutaneous Electric Nerve StimulationAnalgesics, OpioidAnesthetics, LocalAnticonvulsantsAntidepressive AgentsAntineoplastic AgentsAnticonvulsantsAntidepressantsChemotherapy toxicityOpioidsPainPeripheral neuropathy

Identifiers

PMID25584767
PMCPMC5439219

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.