ArticleACS nano2015
Highly angiogenic peptide nanofibers.
Article in ACS nano, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 79 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
79 citing papers in PubMed.
- Tunable regional targeting of self-assembling peptide nanomaterials in acute myocardial infarction.Advanced nanobiomed research · 2026Article
- Programming angiogenesis with tunable assemblies of multifunctional peptides.Science advances · 2026Article
- Strategies for the vascular patterning of engineered tissues for organ repair.Nature biomedical engineering · 2025Review
- Molecular Dynamics Study on the Influence of the CLK Motif on the Structural Stability of Collagen-Like Peptides Adsorbed on Gold Nanosurfaces.ACS omega · 2025Article
- Recent advances in glycopeptide hydrogels: design, biological functions, and biomedical applications.Frontiers in bioengineering and biotechnology · 2025Review
- A Roadmap of Peptide-Based Materials in Neural Regeneration.Advanced healthcare materials · 2025Review
- Self-Assembly and Wound Healing Activity of Biomimetic Cycloalkane-Based Lipopeptides.ACS applied materials & interfaces · 2024Article
- Structural Consequences of Introducing Bioactive Domains to Designer β-Sheet Peptide Self-Assemblies.Biomacromolecules · 2024Article
- Injectable Peptide Hydrogels Loaded with Murine Embryonic Stem Cells Relieve IschemiaBiomacromolecules · 2024Article
- Antiviral fibrils of self-assembled peptides with tunable compositions.Nature communications · 2024Article
- Applications of hydrogels and nanoparticles in the treatment of traumatic brain injury.Frontiers in bioengineering and biotechnology · 2024Review
- Hydrogel in the Treatment of Traumatic Brain Injury.Biomaterials research · 2024Review
- Extracellular matrix type 0: From ancient collagen lineage to a versatile product pipeline - JellaGel™.Materials today. Bio · 2023Article
- Stability of Nanopeptides: Structure and Molecular Exchange of Self-assembled Peptide Fibers.ACS nano · 2023Article
- Synthetic extracellular matrices with function-encoding peptides.Nature reviews bioengineering · 2023Review
- Tissue engineering modalities in skeletal muscles: focus on angiogenesis and immunomodulation properties.Stem cell research & therapy · 2023Review
- Biomimetic natural biomaterials for tissue engineering and regenerative medicine: new biosynthesis methods, recent advances, and emerging applications.Military Medical Research · 2023Review
- Hydrogels with intrinsic antibacterial activity prepared from naphthyl anthranilamide (NaA) capped peptide mimics.Scientific reports · 2022Article
- Self-assembling Molecular Medicine for the Subacute Phase of Ischemic Stroke.Neurochemical research · 2022Review
- Cells and material-based strategies for regenerative endodontics.Bioactive materials · 2022Review
19 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
Major limitations of current tissue regeneration approaches using artificial scaffolds are fibrous encapsulation, lack of host cellular infiltration, unwanted immune responses, surface degradation preceding biointegration, and artificial degradation byproducts. Specifically, for scaffolds larger than 200-500 μm, implants must be accompanied by host angiogenesis in order to provide adequate nutrient/waste exchange in the newly forming tissue. In the current work, we design a peptide-based self-assembling nanofibrous hydrogel containing cell-mediated degradation and proangiogenic moieties that specifically address these challenges. This hydrogel can be easily delivered by syringe, is rapidly infiltrated by cells of hematopoietic and mesenchymal origin, and rapidly forms an extremely robust mature vascular network. Scaffolds show no signs of fibrous encapsulation and after 3 weeks are resorbed into the native tissue. These supramolecular assemblies may prove a vital paradigm for tissue regeneration and specifically for ischemic tissue disease.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.