ArticleBritish journal of cancer2015
Evaluation of chemoresponse assays as predictive markers.
Article in British journal of cancer, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Evolution of Chemosensitivity and Resistance Assays as Predictors of Clinical Outcomes in Epithelial Ovarian Cancer Patients.Current pharmaceutical design · 2016Review
- Response to comment on: 'evaluation of chemoresponse assays as predictive biomarkers'.British journal of cancer · 2015Article
- Comment on: 'evaluation of chemoresponse assays as predictive markers'.British journal of cancer · 2015Article
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundA chemoresponse assay that can be used to predict which patients will respond to which drugs would be useful in directing treatment. Two new analytic methods to assess the predictive ability of a chemoresponse assay have been proposed by Tian et al.
methodsThree examples in which a hypothetical assay has no predictive ability are considered to evaluate the properties of the proposed analytic methods.
resultsFor these specific examples, the proposed methods incorrectly suggest that the assay is predictive.
conclusionsThe examples presented here demonstrate that it can be challenging to evaluate the predictive value of a chemoresponse assay.
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Registered trials
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