Evidence map›Paper›PMID 25584171›Full record

ReviewGastroenterology and hepatology from bed to bench2015

Introducing biomarker panel in esophageal, gastric, and colon cancers; a proteomic approach.

Mona Zamanian-Azodi, Mostafa Rezaei-Tavirani, Hadi Hasanzadeh, Sara Rahmati Rad, Sona Dalilan

Abstract readReview
In one paragraph

Review in Gastroenterology and hepatology from bed to bench, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Targeting colon cancer via antimicrobial RT2 peptide: a system biology study.Gastroenterology and hepatology from bed to bench · 2023
    Article
  5. Article
  6. Down-regulation of TP53 is a highlighted molecular event in gastric ulcer.Gastroenterology and hepatology from bed to bench · 2022
    Article
  7. Article
  8. Article
  9. Gene screening of colorectal cancers via network analysis.Gastroenterology and hepatology from bed to bench · 2019
    Article
  10. Pharmaceutical Advances and Proteomics Researches.Iranian journal of pharmaceutical research : IJPR · 2019
    Review
  11. Proteomics Applications in Health: Biomarker and Drug Discovery and Food Industry.Iranian journal of pharmaceutical research : IJPR · 2018
    Article
  12. Comparative study of gastric cancer and chronic gastritis via network analysis.Gastroenterology and hepatology from bed to bench · 2018
    Article
  13. Article
  14. Article
  15. Total Oxidant/Antioxidant Status in Sera of Patients with Esophageal Cancer.Medical science monitor : international medical journal of experimental and clinical research · 2017
    Article
  16. Article
  17. Introducing crucial protein panel of gastric adenocarcinoma disease.Gastroenterology and hepatology from bed to bench · 2017
    Article
  18. Article
  19. Network analysis of common genes related to esophageal, gastric, and colon cancers.Gastroenterology and hepatology from bed to bench · 2017
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mona Zamanian-AzodiProteomics Research Center, Faculty of Paramedical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Mostafa Rezaei-TaviraniProteomics Research Center, Faculty of Paramedical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Hadi HasanzadehDepartment of Medical Physics, Semnan University of Medical Sciences, Semnan, Iran.
Sara Rahmati RadDepartment of Cell and Molecular Biology, Faculty of Science, University of Tehran, Tehran, Iran.
Sona DalilanProteomics Research Center, Faculty of Paramedical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer research is an attractive field in molecular biology and medicine. By applying large-scale tools such as advanced genomics and proteomics, cancer diagnosis and treatment have been improved greatly. Cancers of esophagus, gastric, and colon accounted for major health problem globally. Biomarker panel could bring out the accuracy for cancer evaluation tests as it can suggest a group of candidate molecules specified to particular malignancy in a way that distinguishing malignant tumors from benign, differentiating from other diseases, and identifying each stages with high specificity and sensitivity. In this review, a systematic search of unique protein markers reported by several proteomic literatures are classified in their specific cancer type group as novel panels for feasible accurate malignancy diagnosis and treatment. About thousands of introduced proteins were studied; however, a small number of them belonged to a specific kind of malignancy. In conclusion, despite the fact that combinatorial biomarkers appear to be hopeful, more evaluation of them is crucial to achieve the suitable biomarker panel for clinical application. This effort needs more investigations and researches for finding a specific and sensitive panel.

Indexed as

Biomarker panelColon cancerEsophagus cancerGastric cancerProteomics

Identifiers

PMID25584171
PMCPMC4285927

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.