ReviewClinical ophthalmology (Auckland, N.Z.)2015
The relationship between Graves' ophthalmopathy and dry eye syndrome.
Review in Clinical ophthalmology (Auckland, N.Z.), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 55 citations in OpenAlex.
- A clinical study of topical treatment for thyroid-associated ophthalmopathy with dry eye syndrome.BMC ophthalmology · 2023Trial
- Post Hoc MRI Analysis of Orbital Soft Tissue Volumes Pre- and Post-Teprotumumab in Patients with Chronic, Low-Activity Thyroid Eye Disease.Ophthalmology and therapy · 2026Article
- Clinical characteristics of dry eye patients with thyroid disorders: a cross-sectional study.BMC ophthalmology · 2025Article
- Cornea Oculomics: A Clinical Blueprint for Extending Corneal Diagnostics and Artificial Intelligence in Systemic Health Insights.Diagnostics (Basel, Switzerland) · 2025Review
- Association between statin use and dry eye disease in patients with hyperlipidemia: A population-based retrospective cohort study.Clinical and translational science · 2024Article
- Beyond the Thyroid: A Narrative Review of Extra-thyroidal Manifestations in Hashimoto's Disease.Cureus · 2024Review
- Artificial-Intelligence-Enhanced Analysis of In Vivo Confocal Microscopy in Corneal Diseases: A Review.Diagnostics (Basel, Switzerland) · 2024Review
- Ocular surface and meibomian gland evaluation in euthyroid Graves' ophthalmopathy.International ophthalmology · 2024Article
- Ocular surface disease index in Graves' orbitopathy: a cross-sectional study.Frontiers in endocrinology · 2024Article
- Investigation of Conjunctival Goblet Cell and Tear MUC5AC Protein in Patients With Graves' Ophthalmopathy.Translational vision science & technology · 2023Article
- THE EFFECT OF PALPEBRAL FISSURE HEIGHT IN PRIMARY GAZE POSITION ON TEAR FILM STABILITY.Acta clinica Croatica · 2023Article
- Systemic investigations in dry eye disease.Indian journal of ophthalmology · 2023Article
- Risk factors for development of superior limbic keratoconjunctivitis in thyroid eye disease in Japanese.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023Observational
- Prevalence of Dry Eye Symptoms and Associated Risk Factors among University Students in Poland.International journal of environmental research and public health · 2023Article
- Ocular Surface Disease Related to the Inflammatory and Non-Inflammatory Phases of Thyroid Eye Disease.Clinical ophthalmology (Auckland, N.Z.) · 2023Article
- Article
- Changes in Dry Eye Status after Steroid Pulse and Orbital Radiation Therapies in Active Thyroid Eye Disease.Journal of clinical medicine · 2022Article
- Improvement of Ocular Surface Disease by Lateral Tarsoconjunctival Flap in Thyroid-Associated Orbitopathy Patients with Lid Retraction.Journal of personalized medicine · 2022Article
- Article
- Ocular surface disease in thyroid eye disease: A narrative review.The ocular surface · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundA complex relationship between Graves' ophthalmopathy (GO) and dry eye syndrome exists. New research brings more insight into the association between these two diseases.
methodsA review of the literature was conducted using the query terms "Graves' Ophthalmopathy", "Thyroid Eye Disease", and "Dry Eye" in MedLine (PubMed) and Scopus. A total of 55 papers were reviewed. Case reports were excluded.
conclusionThis review paper shows the close relationship between dry eye syndrome and GO. The underlying mechanisms behind their association suggest mechanical impairment of orbital muscles and immune-mediated lacrimal gland dysfunction as the causes of dry eye in GO patients. However, there are a variety of treatment options available for patients with GO with signs of dry eye, which help combat this issue.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.