Evidence map›Paper›PMID 25584005›Full record

ArticleJournal of clinical oncology : official journal of the American Society of Clinical Oncology2015

Expanded RAS: refining the patient population.

Chloe E Atreya, Ryan B Corcoran, Scott Kopetz

Abstract read
In one paragraph

Article in Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Review
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  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
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  11. Article
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  14. Article
  15. Molecular spectrum ofJournal of gastrointestinal oncology · 2016
    Article
  16. Article
  17. Role of Biologics in Colon Cancer: Still Not Clear.Journal of oncology practice · 2016
    Article
  18. Review
  19. Prognostic factors after resection of colorectal liver metastases following preoperative second-line chemotherapy: Impact of RAS mutations.European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology · 2016
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Chloe E AtreyaHelen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA chloe.atreya@ucsf.edu.
Ryan B CorcoranMassachusetts General Hospital Cancer Center and Harvard Medical School, Boston, MA.
Scott KopetzThe University of Texas MD Anderson Cancer Center, Houston, TX.

Funding

Tumor Heterogeneity and Acquired Resistance to EGFR InhibitionR01CA184843 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI HAMILTON, STANLEY R., KOPETZ, SCOTT · 2015 to 2019
$3.2M
Stress Signaling Pathways and Resistance in Colorectal CancerR01CA172670 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI KOPETZ, SCOTT · 2013 to 2017
$1.6M
Combination Therapy to Improve MAPK Pathway Inhibitor Efficacy in BRAF and KRAS MK08CA166510 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI CORCORAN, RYAN BRUCE · 2013 to 2017
$896k
Targeting of Aberrant Signaling in Patient-Derived Colorectal Cancer ModelsK08CA175153 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI ATREYA, CHLOE E. · 2013 to 2017
$867k
NCI NIH HHS K08 CA166510NCI NIH HHS K08CA175143NCI NIH HHS K08 CA175153NCI NIH HHS R01 CA172670NCI NIH HHS R01CA172670NCI NIH HHS R01 CA184843NCI NIH HHS R01CA184843
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

MutationAntibodies, MonoclonalAntibodies, Monoclonal, HumanizedAntineoplastic Combined Chemotherapy ProtocolsBevacizumabCamptothecinCetuximabCodonErbB ReceptorsFluorouracilGTP PhosphohydrolasesHumansLeucovorinMembrane ProteinsMolecular Targeted TherapyOrganoplatinum CompoundsAntibodies, MonoclonalAntibodies, Monoclonal, HumanizedBevacizumabBRAF protein, humanCamptothecinCetuximabCodonEGFR protein, humanErbB ReceptorsFluorouracilGTP PhosphohydrolasesKRAS protein, humanLeucovorinMembrane ProteinsNRAS protein, humanOrganoplatinum CompoundsPanitumumabProto-Oncogene ProteinsProto-Oncogene Proteins B-rafProto-Oncogene Proteins p21(ras)ras Proteins

Identifiers

PMID25584005
PMCPMC4334773

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.