Evidence map›Paper›PMID 25583423›Full record

ReviewJapanese journal of clinical oncology2015

Ovarian cancer: new developments in clear cell carcinoma and hopes for targeted therapy.

Yoriko Yamashita

Abstract readReview
In one paragraph

Review in Japanese journal of clinical oncology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Fifth Ovarian Cancer Consensus Conference of the Gynecologic Cancer InterGroup (GCIG): clinical trial design for rare ovarian tumours.Annals of oncology : official journal of the European Society for Medical Oncology · 2017
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Clear cell ovarian cancer and endometriosis: is there a relationship?Przeglad menopauzalny = Menopause review · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Yoriko YamashitaDepartment of Experimental Pathology and Tumor Biology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan k46581a@nucc.cc.nagoya-u.ac.jp.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Until recently, ovarian clear cell carcinoma was recognized by its unique morphology and unfavorable patient outcome primarily due to tumor chemoresistance. Recently, specific molecular characteristics of ovarian clear cell carcinoma, such as PI3CA mutation, ARID1a mutation and MET amplification, have been elucidated. In addition, an association between endometriosis and the tumor has also been a focus of research in recent years. The aim of this review is to discuss the specificity and importance of molecular changes and various intriguing points that are not solved until today. Finally, future aspects, including hopes for the development of novel therapies, are discussed.

Indexed as

Adenocarcinoma, Clear CellOvarian NeoplasmsDNA-Binding ProteinsEndometriosisFemaleGene AmplificationHumansMolecular Targeted TherapyMutationNeoplasm StagingNuclear ProteinsProto-Oncogene Proteins c-metTranscription FactorsARID1A protein, humanDNA-Binding ProteinsMET protein, humanNuclear ProteinsPI3KCA protein, humanProto-Oncogene Proteins c-metTranscription FactorsARID1A mutationMET amplificationovarian clear cell carcinomaPI3CA mutationtargeted therapy

Identifiers

PMID25583423
PMCPMC4412138

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.