ArticleScientific reports2015
No DNA damage response and negligible genome-wide transcriptional changes in human embryonic stem cells exposed to terahertz radiation.
Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.
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Who cites it
37 citing papers in PubMed, 1 synthesis or guideline pooled it, 80 citations in OpenAlex.
- Non-Thermal Effects of Terahertz Radiation on Gene Expression: Systematic Review and Meta-Analysis.Genes · 2024Pooled it
- 3.75 THz Repetitive Radiation Regulates Collagen Metabolism in Human Fetal Scleral Fibroblasts.Cells · 2026Article
- Terahertz Modulation of Biomolecular Dynamics: Physical Mechanisms, Biological Implications, and Future Challenges.Research (Washington, D.C.) · 2026Review
- Response of pheochromocytoma neuronal cells to varying intensity of continuous wave terahertz radiation.Journal of synchrotron radiation · 2025Article
- Article
- Assessment of the Safety of THz Irradiation on the Morphofunctional Characteristics of Rabbit Corneas.Bulletin of experimental biology and medicine · 2025Article
- 0.46 Terahertz wave irradiation inhibit transcription reaction in liposomes.Scientific reports · 2025Article
- Assessment of the general clinical condition and functional properties of the eyes of rabbits after THz irradiation.Biomedical optics express · 2025Article
- Effect of terahertz radiation on cells and cellular structures.Frontiers of optoelectronics · 2025Review
- Transcriptomic Analysis of Blood Collagen-Induced Arthritis Mice Exposed to 0.1 THz Reveals Inhibition of Genes and Pathways Involved in Rheumatoid Arthritis.International journal of molecular sciences · 2024Article
- The biological effects of terahertz wave radiation-induced injury on neural stem cells.iScience · 2023Article
- Review
- Spectral Characteristics and Functional Responses of Phospholipid Bilayers in the Terahertz Band.International journal of molecular sciences · 2023Article
- Sensitivity of Neuroblastoma and Induced Neural Progenitor Cells to High-Intensity THz Radiation.International journal of molecular sciences · 2023Article
- Specific Features of the Proteomic Response of Thermophilic BacteriumInternational journal of molecular sciences · 2022Article
- The Spatial Distribution of Renal Fibrosis Investigated by Micro-probe Terahertz Spectroscopy System.Diagnostics (Basel, Switzerland) · 2022Article
- A Comparative Study on the Viability of Normal and Cancerous Cells upon Irradiation with a Steady Beam of THz Rays.Life (Basel, Switzerland) · 2022Article
- Universal Virucidal Activity of Calcium Bicarbonate Mesoscopic Crystals That Provides an Effective and Biosafe Disinfectant.Microorganisms · 2022Article
- Effects of high intensity non-ionizing terahertz radiation on human skin fibroblasts.Biomedical optics express · 2021Article
- Cellular effects of terahertz waves.Journal of biomedical optics · 2021Review
Corrections and comments
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Authors and funding
9 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Terahertz (THz) radiation was proposed recently for use in various applications, including medical imaging and security scanners. However, there are concerns regarding the possible biological effects of non-ionising electromagnetic radiation in the THz range on cells. Human embryonic stem cells (hESCs) are extremely sensitive to environmental stimuli, and we therefore utilised this cell model to investigate the non-thermal effects of THz irradiation. We studied DNA damage and transcriptome responses in hESCs exposed to narrow-band THz radiation (2.3 THz) under strict temperature control. The transcription of approximately 1% of genes was subtly increased following THz irradiation. Functional annotation enrichment analysis of differentially expressed genes revealed 15 functional classes, which were mostly related to mitochondria. Terahertz irradiation did not induce the formation of γH2AX foci or structural chromosomal aberrations in hESCs. We did not observe any effect on the mitotic index or morphology of the hESCs following THz exposure.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.