ArticleMolecular plant pathology2015
The signalling mucin Msb2 regulates surface sensing and host penetration via BMP1 MAP kinase signalling in Botrytis cinerea.
Article in Molecular plant pathology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed.
- The SsSmk1-SsSom1-SsMsb2 Pathway Regulates Infection Cushion Formation and Pathogenicity in Sclerotinia sclerotiorum.Molecular plant pathology · 2025Article
- Establishment of a Mutant Library for Infection Cushion Development and Identification of a Key Regulatory Gene inJournal of fungi (Basel, Switzerland) · 2024Article
- Conserved signaling modules regulate filamentous growth in fungi: a model for eukaryotic cell differentiation.Genetics · 2024Review
- Ecological inducers of the yeast filamentous growth pathway reveal environment-dependent roles for pathway components.mSphere · 2023Article
- Surface wax in the ancestral grapevine Vitis sylvestris correlate with partial resistance to Powdery Mildew.BMC plant biology · 2023Article
- Cell Wall Integrity and Its Industrial Applications in Filamentous Fungi.Journal of fungi (Basel, Switzerland) · 2022Review
- A dialogue-like cell communication mechanism is conserved in filamentous ascomycete fungi and mediates interspecies interactions.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Transcriptional Network inJournal of fungi (Basel, Switzerland) · 2022Article
- SsAGM1-Mediated Uridine Diphosphate-Frontiers in microbiology · 2022Article
- Cell-free supernatant ofFrontiers in microbiology · 2022Article
- Pathogenic Process-Associated Transcriptome Analysis ofInternational journal of genomics · 2022Article
- Mucin Msb2 cooperates with the transmembrane protein Sho1 in various plant surface signal sensing and pathogenic processes in the poplar anthracnose fungus Colletotrichum gloeosporioides.Molecular plant pathology · 2021Article
- Regulation of biotic interactions and responses to abiotic stresses by MAP kinase pathways in plant pathogenic fungi.Stress biology · 2021Review
- Cyclophilin BcCyp2 Regulates Infection-Related Development to Facilitate Virulence of the Gray Mold FungusInternational journal of molecular sciences · 2021Article
- Gene diversity explains variation in biological features of insect killing fungus, Beauveria bassiana.Scientific reports · 2021Article
- Characterization of the Role of a Non-GPCR Membrane-Bound CFEM Protein in the Pathogenicity and Germination ofMicroorganisms · 2020Article
- ThemSphere · 2019Article
- The MAPK kinase BcMkk1 suppresses oxalic acid biosynthesis via impeding phosphorylation of BcRim15 by BcSch9 in Botrytis cinerea.PLoS pathogens · 2018Article
- Article
- Mitogen-activated protein kinase signaling in plant pathogenic fungi.PLoS pathogens · 2018Article
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4 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Botrytis cinerea is a necrotrophic fungus that infects a wide range of fruit, vegetable and flower crops. Penetration of the host cuticle occurs via infection structures that are formed in response to appropriate plant surface signals. The differentiation of these structures requires a highly conserved mitogen-activated protein (MAP) kinase cascade including the MAP kinase BMP1. In yeast and several plant-pathogenic fungi, the signalling mucin Msb2 has been shown to be involved in surface recognition and MAP kinase activation. In this study, a B. cinerea msb2 mutant was generated and characterized. The mutant showed normal growth, sporulation, sclerotia formation and stress resistance. In the absence of nutrients, abnormal germination with multiple germ tubes was observed. In the presence of sugars, normal germination occurred, but msb2 germlings were almost unable to form appressoria or infection cushions on hard surfaces. Nevertheless, the msb2 mutant showed only a moderate delay in lesion formation on different host plants, and formed expanding lesions similar to the wild-type. Although the wild-type showed increasing BMP1 phosphorylation during the first hours of germination on hard surfaces, the phosphorylation levels in the msb2 mutant were strongly reduced. Several genes encoding secreted proteins were found to be co-regulated by BMP1 and Msb2 during germination. Taken together, B. cinerea Msb2 is likely to represent a hard surface sensor of germlings and hyphae that triggers infection structure formation via the activation of the BMP1 MAP kinase pathway.
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