Evidence map›Paper›PMID 25582849›Full record

SynthesisJournal of clinical hypertension (Greenwich, Conn.)2015

The role of continuous positive airway pressure in blood pressure control for patients with obstructive sleep apnea and hypertension: a meta-analysis of randomized controlled trials.

Xinyu Hu, Jinqi Fan, Shaojie Chen, Yuehui Yin, Bernhard Zrenner

Registry-linked trialOpen access · bronzeAbstract readMeta-AnalysisReview
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Journal of clinical hypertension (Greenwich, Conn.), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03753633 (Efficiency of Speech Therapy in Resistant Hypertensive Patients With Mild Obstructive Sleep Apnea Syndrome), which is not on this map. Cited by 73 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
73citing papers in PubMed, 7 pooled it
12.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03753633 naunknown statusnot on this mapstarted 2017, after this paper: background citation

Efficiency of Speech Therapy in Resistant Hypertensive Patients With Mild Obstructive Sleep Apnea Syndrome

TypeinterventionalSponsorUniversidade Federal do Rio de JaneiroRan2017 to 2019Enrolled50ConditionsSleep Apnea, Obstructive, Hypertension SecondaryArmsSpeech therapy, Control
3 · Its place in the literature

Who cites it

73 citing papers in PubMed, 7 syntheses or guidelines pooled it, 155 citations in OpenAlex.

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  20. Comparative Efficacy of Continuous Positive Airway Pressure and Antihypertensive Medications in Obstructive Sleep Apnea-Related Hypertension: A Narrative Review.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2025
    Review

13 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Xinyu HuDepartment of Cardiology, the Chongqing Cardiac Arrhythmias Service Center, the Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Jinqi Fan
Shaojie Chen
Yuehui Yin
Bernhard Zrenner
Chongqing Medical University · CNSecond Affiliated Hospital of Chongqing Medical University · CNShanghai First People's Hospital · CNUniversity of Applied Sciences Landshut · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to review the effect of continuous positive airway pressure (CPAP) on blood pressure (BP) in patients with obstructive sleep apnea (OSA) and hypertension. Biomedical databases were searched for randomized controlled trials (RCTs) comparing CPAP with control among these patients. Seven RCTs reporting 24-hour ambulatory BP were identified for meta-analysis. CPAP was associated with significant reductions in 24-hour ambulatory systolic blood pressure (SBP) (-2.32 mm Hg; 95% confidence interval [CI], -3.65 to -1.00) and diastolic blood pressure (DBP) (-1.98 mm Hg; 95% CI, -2.82 to -1.14). CPAP led to more significant improvement in nocturnal SBP than that in diurnal SBP. Subgroup analysis showed that patients with resistant hypertension or receiving antihypertensive drugs benefited most from CPAP. Meta-regression indicated that CPAP compliance, age, and baseline SBP were positively correlated with decrease in 24-hour DBP, but not reduction in 24-hour SBP.

Indexed as

Continuous Positive Airway PressureAdolescentAdultAgedAged, 80 and overBlood PressureBlood Pressure Monitoring, AmbulatoryCircadian RhythmComorbidityFemaleHumansHypertensionMaleMiddle AgedRandomized Controlled Trials as TopicSleep Apnea, Obstructive

Identifiers

PMID25582849
PMCPMC8032019
OpenAlexW2046481528

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.