Evidence map›Paper›PMID 25582647›Full record

ReviewInfectious disease clinics of North America2015

The epidemiology of Clostridium difficile infection inside and outside health care institutions.

Dale N Gerding, Fernanda C Lessa

Abstract readReview
In one paragraph

Review in Infectious disease clinics of North America, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed.

  1. Investigating in-hospital transmission ofJournal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada · 2025
    Article
  2. iMetaOmics · 2025
    Review
  3. Infection and drug resistance · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Characterization of community-acquiredFrontiers in microbiology · 2023
    Article
  9. Article
  10. Review
  11. Biomolecular NMR assignments · 2021
    Article
  12. Epidemiology of community-acquired and recurrentTherapeutic advances in gastroenterology · 2021
    Review
  13. Article
  14. Article
  15. Lipid Species in the GI Tract are Increased by the Commensal FungusJournal of fungi (Basel, Switzerland) · 2020
    Article
  16. Article
  17. Article
  18. Trends in U.S. Burden ofThe New England journal of medicine · 2020
    Article
  19. Clinics in colon and rectal surgery · 2020
    Review
  20. The xenobiotic sensing pregnane X receptor regulates tissue damage and inflammation triggered by C difficile toxins.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Dale N GerdingDepartment of Medicine, Loyola University Chicago Stritch School of Medicine, 2160 S 1st Avenue, Maywood, IL 60153, USA; Research Service, Edward Hines, Jr. Veterans Affairs Hospital, 5000 South Fifth Avenue, Building 1, Room 347, Hines, IL 60141, USA. Electronic address: dale.gerding2@va.gov.
Fernanda C LessaDivision of Healthcare Quality Promotion, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, 1600 Clifton Road, Atlanta, GA 30329, USA.

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

This article describes the global changes in Clostridium difficile epidemiology since the late twentieth century and into the twenty-first century when the new epidemic strain BI/NAP1/027 emerged. The article provides an overview of how understanding of C difficile epidemiology has rapidly evolved since its initial association with colitis in 1974. It also discusses how C difficile has spread across the globe, the role of asymptomatic carriers in disease transmission, the increased recognition of C difficile outside health care settings, the changes in epidemiology of C difficile infection in children, and the risk factors for disease.

Indexed as

Clostridioides difficileHealth FacilitiesClostridium InfectionsCross InfectionGastrointestinal DiseasesHumansIncidenceRisk FactorsVirulenceClostridium difficile infectionCommunity associatedHealth care associatedRisk factorsStrain type

Identifiers

PMID25582647
PMCPMC10924674

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.