ArticleMolecular psychiatry2015
Psychiatric blood biomarkers: avoiding jumping to premature negative or positive conclusions.
Article in Molecular psychiatry, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
38 citing papers in PubMed.
- Effect of memantine on C-reactive protein and lipid profiles in bipolar disorder.Journal of affective disorders · 2017Trial
- From case-control averages to validated subgroups: Interpreting inflammatory and neuroaxonal-injury biomarkers in schizophrenia and major depression.Brain, behavior, & immunity - health · 2026Review
- A Study of Candidate Genes Associated with Suicide Attempts in the Kazakh Population in Astana, Kazakhstan.International journal of molecular sciences · 2026Article
- Peripheral NORAD lncRNA and MARCKS mRNA expression in suicidal adolescents: a case-control studyMolecular biology reports · 2025Article
- Methylation in MAD1L1 is associated with the severity of suicide attempt and phenotypes of depression.Clinical epigenetics · 2023Article
- Exposure to war and conflict: The individual and inherited epigenetic effects on health, with a focus on post-traumatic stress disorder.Frontiers in epidemiology · 2023Review
- Blending oxytocin and dopamine with everyday creativity.Scientific reports · 2021Article
- Clustering suicidal phenotypes and genetic associations with brain-derived neurotrophic factor in patients with substance use disorders.Translational psychiatry · 2021Article
- Peripheral Biomarkers in DSM-5 Anxiety Disorders: An Updated Overview.Brain sciences · 2020Review
- Towards precision medicine for stress disorders: diagnostic biomarkers and targeted drugs.Molecular psychiatry · 2020Article
- Convergence of recent GWAS data for suicidality with previous blood biomarkers: independent reproducibility using independent methodologies in independent cohorts.Molecular psychiatry · 2020Review
- Research Domain Criteria scores estimated through natural language processing are associated with risk for suicide and accidental death.Depression and anxiety · 2019Article
- SKA2/FAM33A: A novel gene implicated in cell cycle, tumorigenesis, and psychiatric disorders.Genes & diseases · 2019Review
- Multimodel inference for biomarker development: an application to schizophrenia.Translational psychiatry · 2019Article
- Common genes associated with antidepressant response in mouse and man identify key role of glucocorticoid receptor sensitivity.PLoS biology · 2017Article
- Genomewide association studies of suicide attempts in US soldiers.American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics · 2017Article
- Fish Oil Prevents Lipopolysaccharide-Induced Depressive-Like Behavior by Inhibiting Neuroinflammation.Molecular neurobiology · 2017Article
- Neuropathology of suicide: recent findings and future directions.Molecular psychiatry · 2017Review
- Precision medicine for suicidality: from universality to subtypes and personalization.Molecular psychiatry · 2017Article
- The Life Span Model of Suicide and Its Neurobiological Foundation.Frontiers in neuroscience · 2017Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Blood biomarkers may provide a scientifically useful and clinically usable peripheral signal in psychiatry, as they have been doing for other fields of medicine. Jumping to premature conclusions, negative or positive, can create confusion in this field. Reproducibility is a hallmark of good science. We discuss some recent examples from this dynamic field, and show some new data in support of previously published biomarkers for suicidality (SAT1, MARCKS and SKA2). Methodological clarity and rigor in terms of biomarker discovery, validation and testing is needed. We propose a set of principles for what constitutes a good biomarker, similar in spirit to the Koch postulates used at the birth of the field of infectious diseases.
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Registered trials
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