Observational studyThe British journal of radiology2015
Clinical observation of the adverse drug reactions caused by non-ionic iodinated contrast media: results from 109,255 cases who underwent enhanced CT examination in Chongqing, China.
Observational study in The British journal of radiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 48 citations in OpenAlex.
- A systematic review of the incidence of hypersensitivity reactions and post-contrast acute kidney injury after ioversol in more than 57,000 patients: part 1-intravenous administration.European radiology · 2022Pooled it
- Negative Predictive Value of Allergologic Work-Up with Iodinated Contrast Media in 'Real-Life' Practice.Journal of clinical medicine · 2026Article
- Data Mining of Adverse Reactions to Iodinated Contrast Media Based on a Municipal Spontaneous Reporting System in China.Current medical science · 2025Article
- Association between acute adverse reactions to iodinated contrast media and anxiety in patients undergoing contrast-enhanced CT examination.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2023Article
- Stratified assessment and warning regimen for prevention of acute adverse reactions to iodinated contrast media: results of 150,343 cases in a tertiary hospital.Medical & biological engineering & computing · 2023Article
- Application report of automatic unlocking baseplate in radiotherapy.Journal of applied clinical medical physics · 2022Article
- Hypersensitivity Reactions to Iodinated Contrast Media.Biomedicines · 2022Review
- Change the preprocedural fasting policy for contrast-enhanced CT: results of 127,200 cases.Insights into imaging · 2022Article
- Preprocedural fasting for contrast-enhanced CT: when experience meets evidence.Insights into imaging · 2021Review
- Acute Urticaria in Inpatients Undergoing Non-emergent Coronary Angiography With Corticosteroid Prophylaxis: A Retrospective Study.Frontiers in medicine · 2021Article
- Can the lower rate of CT- or MRI-related adverse drug reactions to contrast media due to stricter limitations on patients undergoing contrast-enhanced CT or MRI?Dento maxillo facial radiology · 2020Article
- The effect of preparative solid food status on the occurrence of nausea, vomiting and aspiration symptoms in enhanced CT examination: prospective observational study.The British journal of radiology · 2018Observational
- Nausea and vomiting after exposure to non-ionic contrast media: incidence and risk factors focusing on preparatory fasting.The British journal of radiology · 2018Article
- Imaging of acute pulmonary embolism: an update.Cardiovascular diagnosis and therapy · 2018Review
- Clinical observation of adverse drug reactions to non-ionic iodinated contrast media in population with underlying diseases and risk factors.The British journal of radiology · 2017Article
- Retrospective analysis of non-laboratory-based adverse drug reactions induced by intravenous radiocontrast agents in a Joint Commission International-accredited academic medical center hospital in China.Therapeutics and clinical risk management · 2017Article
- How often are Patients Harmed When They Visit the Computed Tomography Suite? A Multi-year Experience, in Incident Reporting, in a Large Academic Medical Center.European radiology · 2016Article
- Safety enhancement in adult body computed tomography scanning: comparison of iodixanol versus iohexol.SpringerPlus · 2016Article
- Safety incident reporting in emergency radiology: analysis of 1717 safety incident reports.Emergency radiology · 2015Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo analyse the pattern and factors that influence the incidence of adverse drug reactions (ADRs) induced by non-ionic iodinated contrast media and to evaluate their safety profiles.
methodsData from 109,255 cases who underwent enhanced CT examination from 1 January 2008 to 31 August 2013 were analysed. ADRs were classified according to the criteria issued by the American College of Radiology and the Chinese Society of Radiology.
resultsA total of 375 (0.34%) patients had ADRs, including 281 mild (0.26%); 80 moderate (0.07%); and 14 severe (0.01%) ADRs; no death was found. 302 (80.53%) of the ADRs occurred within 15 min after examination. Patients aged 40-49 years (204 cases, 0.43%; p < 0.01) or who underwent coronary CT angiography (93 cases, 0.61%; p < 0.01) were at a higher risk of ADRs. Female patients (180 cases, 0.40%; p < 0.01) or outpatients had significantly higher incidence rates of ADRs. The symptoms and signs of most of the ADRs were resolved spontaneously within 24 h after appropriate treatment without sequelae.
conclusionThe occurrence of ADRs is caused by the combined effects of multiple factors. The ADRs induced by non-ionic iodinated contrast media are mainly mild ones, while moderate or severe ADRs are relatively rare, suggesting that enhanced CT examination with non-ionic iodinated contrast media is highly safe, and severe adverse events will seldom occur under appropriate care. ADVANCES IN KNOWLEDGE: The study included 109,255 patients enrolled in various types of enhanced CT examinations, which could reflect ADR conditions and regulations in Chinese population accurately and reliably.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.