ArticleJournal of cardiac failure2015
Ventricular conduction defects and the risk of incident heart failure in the Atherosclerosis Risk in Communities (ARIC) Study.
Article in Journal of cardiac failure, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
17 citing papers in PubMed, 25 citations in OpenAlex.
- Prevalence and Clinical Impact of Pathogenic Variants in Cardiomyopathy Genes Among Individuals with Cardiac Conduction Disorders.medRxiv : the preprint server for health sciences · 2026Article
- Left Bundle Branch Block as a Risk Factor for Heart Failure.JAMA network open · 2025Article
- Revisiting Abnormalities of Ventricular Depolarization: Redefining Phenotypes and Associated Outcomes Using Tree-Based Dimensionality Reduction.Journal of the American Heart Association · 2025Article
- Large Language Model-informed ECG Dual Attention Network for Heart Failure Risk Prediction.IEEE transactions on big data · 2025Article
- Physicians and Machine-Learning Algorithm Performance in Predicting Left-Ventricular Systolic Dysfunction from a Standard 12-Lead-Electrocardiogram.Journal of clinical medicine · 2022Article
- Delayed intrinsicoid deflection: Electrocardiographic harbinger of heart disease.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2022Review
- Left bundle pacing in transposition of the great arteries with previous atrial redirection operation.HeartRhythm case reports · 2022Article
- ECG-AI: electrocardiographic artificial intelligence model for prediction of heart failure.European heart journal. Digital health · 2021Article
- Adult height and incidence of atrial fibrillation and heart failure in older men: The British Regional Heart Study.International journal of cardiology. Heart & vasculature · 2021Article
- Prevalence of heart disease in patients with mitochondrial abnormalities on skeletal muscle biopsy.Annals of clinical and translational neurology · 2021Article
- Article
- What Should Be Done With the Asymptomatic Patient With Right Bundle Branch Block?Journal of the American Heart Association · 2020Article
- The association of QT interval components with atrial fibrillation.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2018Article
- Nonalcoholic Fatty Liver Disease (NAFLD) and Risk of Cardiac Arrhythmias: A New Aspect of the Liver-heart Axis.Journal of clinical and translational hepatology · 2017Review
- Electrocardiographic Predictors of Heart Failure With Reduced Versus Preserved Ejection Fraction: The Multi-Ethnic Study of Atherosclerosis.Journal of the American Heart Association · 2017Article
- Electrocardiographic Time to Intrinsicoid Deflection and Heart Failure: The Multi-Ethnic Study of Atherosclerosis.Clinical cardiology · 2016Article
- Ventricular conduction abnormalities as predictors of long-term survival in acute de novo and decompensated chronic heart failure.ESC heart failure · 2016Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundWe evaluated the risk of incident heart failure (HF) associated with various categories of ventricular conduction defects (VCDs) and examined the impact of QRS duration on the risk of HF. METHODS AND
resultsThis analysis included 14,478 participants from the Atherosclerosis Risk in Communities (ARIC) study who were free of HF at baseline. VCDs (n = 377) were categorized into right and left bundle branch blocks (RBBB and LBBB, respectively), bifascicular BBB (RBBB with fascicular block), indeterminate-type VCD (IVCD), and pooled VCD group excluding lone RBBB. During an average of 18 years' follow-up, 1,772 participants were hospitalized for incident HF. Compared with no VCD, LBBB and pooled VCD were strongly associated with increased risk of incident HF (multivariable hazard ratios 2.87 and 2.29, respectively). Compared with no VCD with QRS duration <100 ms, HF risk was 1.17-fold for the no VCD group with QRS duration 100-119 ms, 1.97-fold for the pooled VCD group with QRS duration 120-139 ms, and 3.25-fold for the pooled VCD group with QRS duration ≥140 ms. HF risk for the pooled VCD group remained significant (1.74-fold for QRS duration 120-139 ms and 2.81-fold for QRS duration ≥140 ms) in the subgroup free from cardiovascular disease at baseline. Lone RBBB was not associated with incident HF.
conclusionsVCDs except for isolated RBBB are strong predictors of incident HF, and HF risk is further increased as the QRS duration is prolonged >140 ms.
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Registered trials
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