Evidence map›Paper›PMID 25581535›Full record

ArticleHuman vaccines & immunotherapeutics2014

Meeting report VLPNPV: Session 5: Plant based technology.

Lydia R Meador, Tsafrir S Mor

Open access · bronzeAbstract readConference Proceedings
In one paragraph

Article in Human vaccines & immunotherapeutics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Lydia R Meadora School of Life Sciences and The Biodesign Institute ; Arizona State University ; Tempe , AZ USA.
Tsafrir S Mor
Tempe Union High School District · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The VLPNPV 2014 Conference that was convened at the Salk institute was the second conference of its kind to focus on advances in production, purification, and delivery of virus-like particles (VLPs) and nanoparticles. Many exciting developments were reported and discussed in this interdisciplinary arena, but here we report specifically on the contributions of plant-based platforms to VLP vaccine technology as reported in the section of the conference devoted to the topic as well in additional presentations throughout the meeting. The increasing popularity of plant production platforms is due to their lower cost, scalability, and lack of contaminating animal pathogens seen with other systems. Reports include production of complex VLPs consisting of 4 proteins expressed at finely-tuned expression levels, a prime-boost strategy for HIV vaccination using plant-made VLPs and a live viral vector, and the characterization and development of plant viral nanoparticles for use in cancer vaccines, drug delivery, and bioimaging.

Indexed as

Bluetongue virusCapsid Proteinsgag Gene Products, Human Immunodeficiency VirusHepatitis B Core AntigensHumansNanoparticlesPlantsVaccines, Virus-Like ParticleCapsid Proteinsgag Gene Products, Human Immunodeficiency VirusHepatitis B Core AntigensVaccines, Virus-Like ParticleAb, antibodybluetongue virusBPV, bovine papillomavirusBTV, Bluetongue virusc-Erbb-2 (human epidermal growth factor receptor 2)cowpea mosaic virusCPMV, cowpea mosaic virusELISA, enzyme-linked immunosorbent assayHBV, Hepatitis B virusHepatitis B core antigenHER2, human epidermal growth factor receptor 2 (also called c-ErbB-2)HIV-1HIV, human immunodeficiency virusHT, HyperTransIg, immunoglobulini.p., intraperitoneallive viral vectorsMPR, membrane proximal regionNPV, nano-particle vaccinePEG, polyethylene glycolpotato virus XPVX, potato virus XSNP, spherical nanoparticleTMV, tobacco mosaic virustobacco mosaic virusUTR, untranslated regionviral nanoparticlesvirus-like particlesVLP, virus-like particleVNP, viral nanoparticle

Identifiers

PMID25581535
PMCPMC5443066
OpenAlexW2094609232

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.