Evidence map›Paper›PMID 25581082›Full record

ArticleClinical transplantation2015

Concerns of ABO incompatible and crossmatch-positive potential donors and recipients about participating in kidney exchanges.

James R Rodrigue, Ruthanne Leishman, Tanya Vishnevsky, Amy Evenson, Didier A Mandelbrot

Abstract read
In one paragraph

Article in Clinical transplantation, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

James R RodrigueCenter for Transplant Outcomes and Quality Improvement, The Transplant Institute, Beth Israel Deaconess Medical Center, Boston, MA, USA; Harvard Medical School, Boston, MA, USA.
Ruthanne Leishman
Tanya Vishnevsky
Amy Evenson
Didier A Mandelbrot

Funding

Kidney Donor Outcomes Cohort (KDOC) StudyR01DK085185 · NIDDK · BETH ISRAEL DEACONESS MEDICAL CENTER · PI MANDELBROT, DIDIER A, RODRIGUE, JAMES R · 2011 to 2014
$2.8M
House Calls and Decision Support: Increasing Access to Live Donor TransplantationR01DK098727 · NIDDK · BETH ISRAEL DEACONESS MEDICAL CENTER · PI RODRIGUE, JAMES R · 2012 to 2016
$1.3M
NIDDK NIH HHS R01 DK085185NIDDK NIH HHS R01DK085185NIDDK NIH HHS R01 DK098727
6 · The paper itself

Abstract

Kidney paired exchanges (KPEs) have increased, yet are still underutilized. This study aimed to develop tools for assessing KPE concerns, identify predictors of KPE concerns, and describe common KPE concerns among potential living donors (LDs) and intended recipients. Incompatible former potential LDs (n = 135) and intended recipients (n = 83) retrospectively completed questionnaires to assess KPE concerns. Healthcare system distrust also was assessed. A minority (n = 48 or 36.5% of potential LDs; n = 25 or 30.1% of intended recipients) had pursued KPE participation. Of those who pursued KPE participation, 11 (22.9%) and 6 (24.0%) completed KPE donation or transplantation, respectively. The questionnaires for potential LDs and recipients showed good internal consistency and preliminary convergent validity. LDs and patients less willing to pursue KPE reported more KPE concerns. Common KPE concerns for both potential LDs and recipients were related to perceived Distrust/Inequity and Inconvenience/Cost. Multivariate predictors of more KPE concerns were as follows: male gender (t = 4.5, p < 0.001) and more healthcare system distrust (t = 2.5, p = 0.01) for potential LDs; black race (t = 2.1, p = 0.04) and more healthcare system distrust (t = 2.3, p = 0.03) for intended recipients. These findings underscore the importance of addressing concerns potential LDs and patients have about KPE if the true potential of KPE is to be realized.

Indexed as

ABO Blood-Group SystemBlood Group IncompatibilityDonor SelectionAdultAgedBostonFemaleHumansKidney TransplantationLiving DonorsMaleMiddle AgedPatient Acceptance of Health CareRetrospective StudiesSurveys and QuestionnairesABO Blood-Group Systemincompatiblekidney exchangeliving donationpaired kidney donation

Identifiers

PMID25581082
PMCPMC4516385

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.