Evidence map›Paper›PMID 25580688›Full record

ReviewMolecules (Basel, Switzerland)2015

Activity of alkaloids on peptic ulcer: what's new?

Raphaela Francelino do Nascimento, Igor Rafael Praxedes de Sales, Rodrigo de Oliveira Formiga, José Maria Barbosa-Filho, Marianna Vieira Sobral, Josean Fechine Tavares, Margareth de Fátima Formiga Melo Diniz, Leônia Maria Batista

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
3.2field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 32 citations in OpenAlex.

  1. Molecules (Basel, Switzerland) · 2025
    Article
  2. Article
  3. Article
  4. Article
  5. Traditional Persian topical medications for gastrointestinal diseases.Iranian journal of basic medical sciences · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Raphaela Francelino do NascimentoDepartment of Pharmaceutical Sciences, Federal University of Paraiba, João Pessoa 58051-970, PB, Brazil. raphaelafrancelino@gmail.com.
Igor Rafael Praxedes de SalesDepartment of Pharmaceutical Sciences, Federal University of Paraiba, João Pessoa 58051-970, PB, Brazil. igor_caraubas@hotmail.com.
Rodrigo de Oliveira FormigaDepartment of Pharmaceutical Sciences, Federal University of Paraiba, João Pessoa 58051-970, PB, Brazil. rodrigo.formiga@hotmail.com.
José Maria Barbosa-FilhoDepartment of Pharmaceutical Sciences, Federal University of Paraiba, João Pessoa 58051-970, PB, Brazil.
Marianna Vieira SobralDepartment of Pharmaceutical Sciences, Federal University of Paraiba, João Pessoa 58051-970, PB, Brazil. mariannavbs@gmail.com.
Josean Fechine TavaresDepartment of Pharmaceutical Sciences, Federal University of Paraiba, João Pessoa 58051-970, PB, Brazil. josean@ltf.ufpb.br.
Margareth de Fátima Formiga Melo DinizDepartment of Pharmaceutical Sciences, Federal University of Paraiba, João Pessoa 58051-970, PB, Brazil. margareth@ltf.ufpb.br.
Leônia Maria BatistaDepartment of Pharmaceutical Sciences, Federal University of Paraiba, João Pessoa 58051-970, PB, Brazil. leoniab@uol.com.br.
Universidade Federal da Paraíba · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Peptic ulcer is a common disease characterized by lesions that affect the mucosa of the esophagus, stomach and/or duodenum, and may extend into the muscular layer of the mucosa. Natural products have played an important role in the process of development and discovery of new drugs, due to their wide structural diversity and present, mostly specific and selective biological activities. Among natural products the alkaloids, biologically active secondary metabolites, that can be found in plants, animals or microorganisms stand out. The alkaloids are compounds consisting of a basic nitrogen atom that may or may not be part of a heterocyclic ring. This review will describe 15 alkaloids with antiulcer activity in animal models and in vitro studies.

Indexed as

AlkaloidsAnimalsDisease Models, AnimalHumansPeptic UlcerAlkaloids

Identifiers

PMID25580688
PMCPMC6272740
OpenAlexW2060906104

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.