Evidence map›Paper›PMID 25580624›Full record

ReviewAnnual review of physical chemistry2015

Site-specific infrared probes of proteins.

Jianqiang Ma, Ileana M Pazos, Wenkai Zhang, Robert M Culik, Feng Gai

Abstract readReview
In one paragraph

Review in Annual review of physical chemistry, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers.

0numbers the graph read from it
0cells of the map it votes in
70citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

70 citing papers in PubMed.

  1. Article
  2. Propagation of Photoinduced Electric Field Changes Through Phytochrome and their Impact on Conformational Transitions.Chemphyschem : a European journal of chemical physics and physical chemistry · 2025
    Article
  3. Article
  4. Article
  5. Review
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  8. Review
  9. Article
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  15. Article
  16. Article
  17. Copper-catalyzed asymmetric C(spNature communications · 2023
    Article
  18. Increasing Pump-Probe Signal toward Asymptotic Limits.The journal of physical chemistry. B · 2023
    Review
  19. Toward the Next Frontiers of Vibrational Bioimaging.Chemical & biomedical imaging · 2023
    Review
  20. The photophysics of 2-cyanoindole probed by femtosecond spectroscopy.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2023
    Article

10 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jianqiang MaUltrafast Optical Processes Laboratory.
Ileana M Pazos
Wenkai Zhang
Robert M Culik
Feng Gai

Funding

STRUCTURAL BIOLOGY TRAINING PROGRAMT32GM008275 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI WAND, A. JOSHUA · 1988 to 2018
$6.0M
ULTRAFAST OPTICAL PROCESSES LABORATORYP41GM104605 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI GAI, FENG · 2012 to 2017
$5.6M
Spectroscopic Study of Protein Folding DynamicsR01GM065978 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI GAI, FENG · 2002 to 2014
$3.9M
NIGMS NIH HHS GM-008275NIGMS NIH HHS GM-065978NIGMS NIH HHS P41 GM104605NIGMS NIH HHS P41-GM104605NIGMS NIH HHS R01 GM065978NIGMS NIH HHS T32 GM008275
6 · The paper itself

Abstract

Infrared spectroscopy has played an instrumental role in the study of a wide variety of biological questions. However, in many cases, it is impossible or difficult to rely on the intrinsic vibrational modes of biological molecules of interest, such as proteins, to reveal structural and environmental information in a site-specific manner. To overcome this limitation, investigators have dedicated many recent efforts to the development and application of various extrinsic vibrational probes that can be incorporated into biological molecules and used to site-specifically interrogate their structural or environmental properties. In this review, we highlight recent advancements in this rapidly growing research area.

Indexed as

AnimalsHumansModels, MolecularMolecular ProbesProtein ConformationProteinsSpectrophotometry, InfraredMolecular ProbesProteinsinfrared spectroscopyisotope editingsite-specific probeunnatural amino acidvibrational couplingvibrational Stark effect spectroscopy

Identifiers

PMID25580624
PMCPMC4382430

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.