Evidence map›Paper›PMID 25580536›Full record

ArticleInternational journal of molecular sciences2015

MicroRNA expression profiling of lactating mammary gland in divergent phenotype swine breeds.

Jing Peng, Jun-Sheng Zhao, Yi-Fei Shen, Hai-Guang Mao, Ning-Ying Xu

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 32 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jing PengCollege of Animal Sciences, Zhejiang University, Hangzhou 310058, China. pennypeng1987@163.com.
Jun-Sheng ZhaoCollege of Animal Sciences, Zhejiang University, Hangzhou 310058, China. zjs4939@126.com.
Yi-Fei ShenCollege of Animal Sciences, Zhejiang University, Hangzhou 310058, China. 06dwkxsyf@zju.edu.cn.
Hai-Guang MaoCollege of Animal Sciences, Zhejiang University, Hangzhou 310058, China. maohaiguang@163.com.
Ning-Ying XuCollege of Animal Sciences, Zhejiang University, Hangzhou 310058, China. nyxu@zju.edu.cn.
Zhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MicroRNA (miRNA) plays a key role in development and specific biological processes, such as cell proliferation, differentiation, and apoptosis. Extensive studies of mammary miRNAs have been performed in different species and tissues. However, little is known about porcine mammary gland miRNAs. In this study, we report the identification and characterization of miRNAs in the lactating mammary gland in two distinct pig breeds, Jinhua and Yorkshire. Many miRNAs were detected as significantly differentially expressed between the two libraries. Among the differentially expressed miRNAs, many are known to be related to mammary gland development and lactation by interacting with putative target genes in previous studies. These findings suggest that miRNA expression patterns may contribute significantly to target mRNA regulation and influence mammary gland development and peak lactation performance. The data we obtained provide useful information about the roles of miRNAs in the biological processes of lactation and the mechanisms of target gene expression and regulation.

Indexed as

AnimalsFemaleGene Expression ProfilingLactationMammary Glands, AnimalMicroRNAsMolecular Sequence AnnotationReal-Time Polymerase Chain ReactionSequence Analysis, RNASwineMicroRNAs

Identifiers

PMID25580536
PMCPMC4307312
OpenAlexW2021839377

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.