Evidence map›Paper›PMID 25580456›Full record

ArticleTheScientificWorldJournal2014

How do metal ion levels change over time in hip resurfacing patients? A cohort study.

Lucia Savarino, Matteo Cadossi, Eugenio Chiarello, Caterina Fotia, Michelina Greco, Nicola Baldini, Sandro Giannini

Open access · goldAbstract read
In one paragraph

Article in TheScientificWorldJournal, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. The Effect of Implant Size on Fretting Currents of Acetabular Cup-Liner Tapers During in Vitro Cyclic Loading.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2025
    Article
  3. Trace Elements-Role in Joint Function and Impact on Joint Diseases.International journal of molecular sciences · 2025
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Lucia SavarinoLaboratory for Orthopaedic Pathophysiology and Regenerative Medicine, Rizzoli Orthopaedic Institute, Via di Barbiano 1/10, 40136 Bologna, Italy.
Matteo CadossiDepartment I of Orthopaedics and Traumatology, Rizzoli Orthopaedic Institute, Via Pupilli 1, 40136 Bologna, Italy ; Bologna University, Via Foscolo 7, 40123 Bologna, Italy.
Eugenio ChiarelloDepartment I of Orthopaedics and Traumatology, Rizzoli Orthopaedic Institute, Via Pupilli 1, 40136 Bologna, Italy.
Caterina FotiaLaboratory for Orthopaedic Pathophysiology and Regenerative Medicine, Rizzoli Orthopaedic Institute, Via di Barbiano 1/10, 40136 Bologna, Italy.
Michelina GrecoLaboratory for Orthopaedic Pathophysiology and Regenerative Medicine, Rizzoli Orthopaedic Institute, Via di Barbiano 1/10, 40136 Bologna, Italy.
Nicola BaldiniLaboratory for Orthopaedic Pathophysiology and Regenerative Medicine, Rizzoli Orthopaedic Institute, Via di Barbiano 1/10, 40136 Bologna, Italy ; Bologna University, Via Foscolo 7, 40123 Bologna, Italy.
Sandro GianniniDepartment I of Orthopaedics and Traumatology, Rizzoli Orthopaedic Institute, Via Pupilli 1, 40136 Bologna, Italy ; Bologna University, Via Foscolo 7, 40123 Bologna, Italy.
Istituto Ortopedico Rizzoli · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metal-on-metal hip resurfacing (MOM-HR) is offered as an alternative to traditional hip arthroplasty for young, active adults with advanced osteoarthritis. Nevertheless, concerns remain regarding wear and corrosion of the bearing surfaces and the resulting increase in metal ion levels. We evaluated three cohorts of patients with Birmingham hip resurfacing (BHR) at an average follow-up of 2, 5, and 9 years. We asked whether there would be differences in ion levels between the cohorts and inside the gender. Nineteen patients were prospectively analyzed. The correlation with clinical-radiographic data was also performed. Chromium, cobalt, nickel, and molybdenum concentrations were measured by atomic absorption spectrophotometry. Chromium and cobalt levels demonstrated a tendency to decrease over time. Such tendency was present only in females. An inverse correlation between chromium, implant size, and Harris hip score was present at short term; it disappeared over time together with the decreased ion levels. The prospective analysis showed that, although metal ion levels remained fairly constant within each patient, there was a relatively large variation between subjects, so mean data in this scenario must be interpreted with caution. The chronic high exposure should be carefully considered during implant selection, particularly in young subjects, and a stricter monitoring is mandatory.

Indexed as

Arthroplasty, Replacement, HipHip ProsthesisProsthesis DesignAdultAgedChromiumCobaltCohort StudiesCorrosionFemaleHip JointHumansMaleMiddle AgedMolybdenumNickelChromiumCobaltMolybdenumNickel

Identifiers

PMID25580456
PMCPMC4279264
OpenAlexW2013094354

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.