ReviewBioMed research international2014
Understanding host-adherent-invasive Escherichia coli interaction in Crohn's disease: opening up new therapeutic strategies.
Review in BioMed research international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed, 58 citations in OpenAlex.
- Current and emerging therapeutic strategies targeting adherent-invasive Escherichia coli in Crohn's disease: a review.Gut pathogens · 2026Review
- Intestinal E. coli-produced yersiniabactin promotes profibrotic macrophages in Crohn's disease.Cell host & microbe · 2025Article
- Biological Activity of Hybrid Vaterite-Pectin Microparticles Towards Bacteria E. coli and Human Neutrophils.Bulletin of experimental biology and medicine · 2024Article
- Isolation and characterization of lytic bacteriophages from various sources in Addis Ababa against antimicrobial-resistant diarrheagenic Escherichia coli strains and evaluation of their therapeutic potential.BMC infectious diseases · 2024Article
- The Efficacy of Selected Probiotic Strains and Their Combination to Inhibit the Interaction of Adherent-InvasiveMicroorganisms · 2024Article
- Comparative diet-gut microbiome analysis in Crohn's disease and Hidradenitis suppurativa.Frontiers in microbiology · 2023Article
- An adherent-invasive Escherichia coli-colonized mouse model to evaluate microbiota-targeting strategies in Crohn's disease.Disease models & mechanisms · 2022Article
- Innovative method to grow the probiotic Lactobacillus reuteri in the omega3-rich microalga Isochrysis galbana.Scientific reports · 2022Article
- Intestinal Claudin-7 deficiency impacts the intestinal microbiota in mice with colitis.BMC gastroenterology · 2022Article
- Prevalence, Abundance, and Virulence of Adherent-InvasiveFrontiers in immunology · 2022Article
- Faster and less invasive tools to identify patients with ileal colonization by adherent-invasive E. coli in Crohn's disease.United European gastroenterology journal · 2021Article
- Therapeutic Advances in Diabetes, Autoimmune, and Neurological Diseases.International journal of molecular sciences · 2021Review
- Bacterial cross talk with gut microbiome and its implications: a short review.Folia microbiologica · 2021Review
- A Novel Strategy to Study the Invasive Capability of Adherent-InvasiveFrontiers in immunology · 2021Article
- The Prevalence of Adherent-InvasiveFrontiers in medicine · 2021Article
- Article
- Decreased Enteric Bacterial Composition and Diversity in South American Crohn's Disease Vary With the Choice of Treatment Strategy and Time Since Diagnosis.Journal of Crohn's & colitis · 2020Article
- Cellular Stress Upregulates Indole Signaling Metabolites in Escherichia coli.Cell chemical biology · 2020Article
- The Effect of Substituted Benzene-Sulfonamides and Clinically Licensed Drugs on the Catalytic Activity of CynT2, a Carbonic Anhydrase Crucial forInternational journal of molecular sciences · 2020Article
- Anion Inhibition Studies of the Beta-Carbonic Anhydrase fromMolecules (Basel, Switzerland) · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A trillion of microorganisms colonize the mammalian intestine. Most of them have coevolved with the host in a symbiotic relationship and some of them have developed strategies to promote their replication in the presence of competing microbiota. Recent evidence suggests that perturbation of the microbial community favors the emergence of opportunistic pathogens, in particular adherent-invasive Escherichia coli (AIEC) that can increase incidence and severity of gut inflammation in the context of Crohn's disease (CD). This review will report the importance of AIEC as triggers of intestinal inflammation, focusing on their impact on epithelial barrier function and stimulation of mucosal inflammation. Beyond manipulation of immune response, restoration of gut microbiota as a new treatment option for CD patients will be discussed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.