Evidence map›Paper›PMID 25580428›Full record

Trial reportBioMed research international2014

Impact of medical and surgical treatment of endometriosis on the cure of endometriosis and pain.

Liselotte Mettler, R Ruprai, Ibrahim Alkatout

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BioMed research international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
5.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.

  1. Clinical practice guidelines for endometriosis in Japan (The 3rd edition).The journal of obstetrics and gynaecology research · 2022
    Guideline
  2. Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Postoperative pain management in obstetrics and gynecologyJournal of the Turkish German Gynecological Association · 2020
    Article
  11. Endometriosis Pain Management: a Review.Current pain and headache reports · 2020
    Review
  12. Endometrial "Scratching" An update and overview of current research.Journal of the Turkish German Gynecological Association · 2020
    Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Liselotte MettlerDepartment of Obstetrics and Gynecology, University Clinics of Schleswig-Holstein, Campus Kiel, Arnold-Heller-Straße 3/24, 24105 Kiel, Germany.
R RupraiDepartment of Obstetrics and Gynecology, University Clinics of Schleswig-Holstein, Campus Kiel, Arnold-Heller-Straße 3/24, 24105 Kiel, Germany.
Ibrahim AlkatoutDepartment of Obstetrics and Gynecology, University Clinics of Schleswig-Holstein, Campus Kiel, Arnold-Heller-Straße 3/24, 24105 Kiel, Germany.
University of Lübeck · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This endometriosis study evaluates three different treatment strategies (hormonal medication, surgical, or combined treatment) and discusses the influence of endometriosis on the cure of this disease and pain relief. Four hundred and fifty patients with genital endometriosis, aged 18-44 years, were randomly distributed to three treatment groups at the first laparoscopy. They were reevaluated at a second-look laparoscopy (D 426/10), one to two months after the three-month hormonal therapy for groups 1 and 3 and five to six months later for group 2 (surgical treatment alone). Outcome data focussed on the recurrence of symptoms and pain. The three treatment options independent of the initial endoscopic endometriosis classification (EEC) stage including deep infiltrating endometriosis (DIE) achieved an overall cure rate of 50% or higher. The highest cure rate of 60% was achieved by the combined treatment, 55% by the exclusively hormonal therapy, and 50% by the exclusively surgical treatment. An overall pregnancy rate between 55% and 65% was achieved with no significant difference in relation to the therapeutical option.

Indexed as

AdolescentAdultEndometriosisFemaleHormonesHumansLaparoscopyPainPregnancyTreatment OutcomeHormones

Identifiers

PMID25580428
PMCPMC4279262
OpenAlexW2161259550

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.