ArticleJournal of menopausal medicine2014
Effect of transdermal estrogen therapy on bone mineral density in postmenopausal korean women.
Article in Journal of menopausal medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Effects of transdermal versus oral hormone replacement therapy in postmenopause: a systematic review.Archives of gynecology and obstetrics · 2023Pooled it
- Combined effects of reproductive and hormone factors and obesity on the prevalence of knee osteoarthritis and knee pain among middle-aged or older Chinese women: a cross-sectional study.BMC public health · 2018Article
- The Effects of Transdermal Estrogen Delivery on Bone Mineral Density in Postmenopausal Women: A Meta-analysis.Iranian journal of pharmaceutical research : IJPR · 2017Article
- Effects of Hormone Therapy on Serum Lipid Levels in Postmenopausal Korean Women.Journal of menopausal medicine · 2015Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo evaluate the effects of transdermal estrogen therapy on bone mineral density (BMD) in postmenopausal Korean women.
methodsA total of 149 healthy postmenopausal women were retrospectively evaluated: 100 were on hormone therapy (HT) and 49 were the control group. For the HT group, 54 applied estrogen transdermally using either a patch (n = 21) or gel (n = 33), and 46 took estrogen orally (conjugated estrogen 0.625 mg or equivalent). Demographic profiles and changes in BMD over two years were compared according to the route of the estrogen.
resultsNo differences were found in age, age at menopause, parity, body mass index, and type of menopause among the oral, transdermal and control groups. Compared with controls, HT significantly increased BMD after 2 years in both the lumbar spine and the total hip. The increases in BMD at both lumbar spine and hip were comparable between the oral and transdermal groups. There were also no differences in BMD changes according to progestogen addition in either the oral or transdermal groups.
conclusionTransdermal estrogen therapy increases BMD, comparable to oral estrogen, in postmenopausal Korean women.
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Registered trials
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