ArticlePreventive nutrition and food science2014
Antioxidant activity of orange flesh and peel extracted with various solvents.
Article in Preventive nutrition and food science, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 127 citations in OpenAlex.
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- Antioxidant Activity and Anti-Inflammatory Effect of Blood Orange By-Products in Treated HT-29 and Caco-2 Colorectal Cancer Cell Lines.Antioxidants (Basel, Switzerland) · 2025Article
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- From by-products to new application opportunities: the enhancement of the leaves deriving from the fruit plants for new potential healthy products.Frontiers in nutrition · 2024Review
- Neuroprotective potential of terpenoid-rich extracts from orange juice by-products obtained by pressurized liquid extraction.Food chemistry: X · 2022Article
- A review of plant metabolites with metal interaction capacity: a green approach for industrial applications.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2021Review
- Impacts of Dietary Supplementations of Orange Peel and Tomato Pomace Extracts as Natural Sources for Ascorbic Acid on Growth Performance, Carcass Characteristics, Plasma Biochemicals and Antioxidant Status of Growing Rabbits.Animals : an open access journal from MDPI · 2021Article
- Optimization of Ultrasound-Assisted Extraction via Sonotrode of Phenolic Compounds from Orange By-Products.Foods (Basel, Switzerland) · 2021Article
- Antioxidant and antimicrobial activities and UPLC-ESI-MS/MS polyphenolic profile of sweet orange peel extracts.Current research in food science · 2021Article
- Influence of drying techniques on bioactive properties, phenolic compounds and fatty acid compositions of dried lemon and orange peel powders.Journal of food science and technology · 2021Article
- Fruits By-Products - A Source of Valuable Active Principles. A Short Review.Frontiers in bioengineering and biotechnology · 2020Review
- Green solvents and Ultrasound-Assisted Extraction of bioactive orange (Citrus sinensis) peel compounds.Scientific reports · 2019Article
- Natural combination of phenolic glycosides from fruits resists pro-oxidant insults to colon cells and enhances intrinsic antioxidant status in mice.Toxicology reports · 2019Article
- DNA protection, antioxidant and xanthine oxidase inhibition activities of polyphenol-enriched fraction ofIranian journal of basic medical sciences · 2018Article
- Extraction and quantification of polyphenols from kinnow (Citrus reticulate L.) peel using ultrasound and maceration techniques.Journal of food and drug analysis · 2017Article
- Effects of temperature, time, and solvent ratio on the extraction of phenolic compounds and the anti-radical activity of Clinacanthus nutans Lindau leaves by response surface methodology.Chemistry Central journal · 2017Article
- Development of functional beverages from blends of Hibiscus sabdariffa extract and selected fruit juices for optimal antioxidant properties.Food science & nutrition · 2016Article
- Impact of different solvents on the recovery of bioactive compounds and antioxidant properties from lemon (Food science and biotechnology · 2016Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this study was to investigate the antioxidant activity of orange (Citrus auranthium) flesh (OF) and peel (OP) extracted with acetone, ethanol, and methanol. Antioxidant potential was examined by measuring total phenolic content (TPC), 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity (RSA), total radical-trapping anti-oxidant potential (TRAP), oxygen radical absorbance capacity (ORAC), and cellular antioxidant activity (CAA). The comet assay was used to determine the protective effects of OF and OP against H2O2-induced DNA damage. TPC was highest in the acetone extracts of OF and OP. DPPH RSA was also higher in the acetone extracts than in the ethanol extracts. The DPPH RSA was highest in the acetone extracts of OF. The TRAP and ORAC values of the all extracts increased in a dose-dependent manner. In the TRAP assay, the acetone extracts of OF and OP had the lowest IC50 values. In the CAA assay, the methanol and acetone extracts of OP had the lowest IC50 values. All of the samples protected against H2O2-induced DNA damage in human leukocytes, as measured by the comet assay, but the acetone extracts of OP had the strongest effect. These results suggest that acetone is the best solvent for the extraction of antioxidant compounds from OF and OP. Furthermore, the high antioxidant activity of OP, which is a by-product of orange processing, suggests that it can be used in nutraceutical and functional foods.
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