Evidence map›Paper›PMID 25580256›Full record

ReviewF1000prime reports2014

Novel therapies for open-angle glaucoma.

Scott M Wentz, Nathaniel J Kim, Jenny Wang, Annahita Amireskandari, Brent Siesky, Alon Harris

Open access · bronzeAbstract readReview
In one paragraph

Review in F1000prime reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
4.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. [Self-relaxation techniques for glaucoma patients. Significance of autogenic training, hypnosis and music therapy].Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft · 2016
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Scott M WentzEugene and Marilyn Glick Eye Institute, Indiana University School of Medicine 1160 W Michigan St, Indianapolis, IN 46202 USA.
Nathaniel J KimEugene and Marilyn Glick Eye Institute, Indiana University School of Medicine 1160 W Michigan St, Indianapolis, IN 46202 USA.
Jenny WangEugene and Marilyn Glick Eye Institute, Indiana University School of Medicine 1160 W Michigan St, Indianapolis, IN 46202 USA.
Annahita AmireskandariEugene and Marilyn Glick Eye Institute, Indiana University School of Medicine 1160 W Michigan St, Indianapolis, IN 46202 USA.
Brent SieskyEugene and Marilyn Glick Eye Institute, Indiana University School of Medicine 1160 W Michigan St, Indianapolis, IN 46202 USA.
Alon HarrisEugene and Marilyn Glick Eye Institute, Indiana University School of Medicine 1160 W Michigan St, Indianapolis, IN 46202 USA.
Indiana University – Purdue University Indianapolis · USIndiana University School of Medicine

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Open-angle glaucoma is a multifactorial optic neuropathy characterized by progressive loss of retinal ganglion cells and their axons. It is an irreversible disease with no established cure. The only currently approved treatment is aimed at lowering intraocular pressure, the most significant risk factor known to date. However, it is now clear that there are other risk factors involved in glaucoma's pathophysiology. To achieve future improvements in glaucoma management, new approaches to therapies and novel targets must be developed. Such therapies may include new tissue targets for lowering intraocular pressure, molecules influencing ocular hemodynamics, and treatments providing neuroprotection of retinal ganglion cells. Furthermore, novel drug delivery systems are in development that may improve patient compliance, increase bioavailability, and decrease adverse side effects.

Identifiers

PMID25580256
PMCPMC4229725
OpenAlexW2322320999

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.