ReviewF1000prime reports2014
Mechanisms of planar cell polarity establishment in Drosophila.
Review in F1000prime reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 43 citations in OpenAlex.
- Nuclear translocation of β-catenin in Wg/Wnt signaling via the IFT-A microtubule-associated complex requires Pasovec/Gid8 proteins.Science advances · 2026Article
- The complex relationship of Wnt-signaling pathways and cilia.Current topics in developmental biology · 2023Article
- Planar cell polarity: intracellular asymmetry and supracellular gradients of Dachsous.Open biology · 2022Article
- Live imaging and conditional disruption of native PCP activity using endogenously tagged zebrafish sfGFP-Vangl2.Nature communications · 2022Article
- The conserved Pelado/ZSWIM8 protein regulates actin dynamics by promoting linear actin filament polymerization.Life science alliance · 2022Article
- Cortical Cyclin A controls spindle orientation during asymmetric cell divisions in Drosophila.Nature communications · 2022Article
- Characterization ofmicroPublication biology · 2022Article
- Distinct overlapping functions for Prickle1 and Prickle2 in the polarization of the airway epithelium.Frontiers in cell and developmental biology · 2022Article
- New mouse models for high resolution and live imaging of planar cell polarity proteins in vivo.Development (Cambridge, England) · 2021Article
- Planar cell polarity in the larval epidermis ofOpen biology · 2020Article
- Diminished Expression of Fat and Dachsous PCP Proteins Impaired Centriole Planar Polarization in Drosophila.Frontiers in genetics · 2019Article
- A switch in the mode of Wnt signaling orchestrates the formation of germline stem cell differentiation niche in Drosophila.PLoS genetics · 2018Article
- Membrane Targeting of Disheveled Can Bypass the Need for Arrow/LRP5.Scientific reports · 2017Article
- The palmitoyltransferase Approximated promotes growth via the Hippo pathway by palmitoylation of Fat.The Journal of cell biology · 2017Article
- Vertebrate Axial Patterning: From Egg to Asymmetry.Advances in experimental medicine and biology · 2017Review
- A Novel Frizzled-Based Screening Tool Identifies Genetic Modifiers of Planar Cell Polarity in Drosophila Wings.G3 (Bethesda, Md.) · 2016Article
- Centriole positioning in epithelial cells and its intimate relationship with planar cell polarity.BioEssays : news and reviews in molecular, cellular and developmental biology · 2016Review
- Airway epithelial homeostasis and planar cell polarity signaling depend on multiciliated cell differentiation.JCI insight · 2016Article
- Review
- Positioning of centrioles is a conserved readout of Frizzled planar cell polarity signalling.Nature communications · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Correct patterning and polarization of epithelial and mesenchymal cells are essential for morphogenesis and function of all organs and organisms. Epithelial cells are generally polarized in two axes: (a) the ubiquitous apical-basal axis and (b) polarity within the plane of the epithelium. The latter is generally referred to as planar cell polarity (PCP) and also is found in several contexts of mesenchymal cell patterning. In Drosophila, all adult structures display PCP features, and two conserved molecular systems (the Fat [Ft]/Dachsous [Ds] system and the Frizzled [Fz]/PCP pathway) that regulate this process have been identified. Although significant progress has been made in dissecting aspects of PCP signaling within cells, much remains to be discovered about the mechanisms of long-range and local PCP cell-cell interactions. Here, we discuss the current models based on Drosophila studies and incorporate recent insights into this long-standing cell and developmental biology problem.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.