ArticleRSC advances2014
Click chemistry facilitates direct labelling and super-resolution imaging of nucleic acids and proteins†Electronic supplementary information (ESI) available. See DOI: 10.1039/c4ra01027bClick here for additional data file.
Article in RSC advances, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- Elucidating structure-function relationships in the mammalian nucleolus.Nature reviews. Molecular cell biology · 2026Review
- Single-molecule localization microscopy imaging of extracellular vesicle DNA in recipient cells.Journal of translational medicine · 2026Article
- Microscopy-based techniques for studying the material properties of biomolecular condensates in the cellular environment.Biophysical reviews · 2025Review
- Article
- RNA Probes for Visualization of Sarcin/ricin Loop Depurination without Background Fluorescence.Chemistry, an Asian journal · 2022Article
- Practical considerations for feature assignment in high-speed AFM of live cell membranes.Biophysics and physicobiology · 2022Article
- In vivo 5-ethynyluridine (EU) labelling detects reduced transcription in Purkinje cell degeneration mouse mutants, but can itself induce neurodegeneration.Acta neuropathologica communications · 2021Article
- Super-resolution mapping of cellular double-strand break resection complexes during homologous recombination.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Super-resolution visualization of distinct stalled and broken replication fork structures.PLoS genetics · 2020Article
- Article
- Imaging tripartite synapses using super-resolution microscopy.Methods (San Diego, Calif.) · 2020Article
- Super-resolution Microscopy for Nanomedicine Research.ACS nano · 2019Article
- Super-resolution microscopy reveals how histone tail acetylation affects DNA compaction within nucleosomes in vivo.Nucleic acids research · 2019Article
- Super-Resolution Microscopy of Chromatin.Genes · 2019Review
- Evaluation and optimisation of unnatural amino acid incorporation and bioorthogonal bioconjugation for site-specific fluorescent labelling of proteins expressed in mammalian cells.Biochemistry and biophysics reports · 2019Article
- Switchable Fluorophores for Single-Molecule Localization Microscopy.Chemical reviews · 2018Review
- Spatiotemporal dynamics of homologous recombination repair at single collapsed replication forks.Nature communications · 2018Article
- Fluorescence Polarization Control for On-Off Switching of Single Molecules at Cryogenic Temperatures.Small methods · 2018Article
- Identification of Vaccinia Virus Replisome and Transcriptome Proteins by Isolation of Proteins on Nascent DNA Coupled with Mass Spectrometry.Journal of virology · 2017Article
- Site-specific fluorescent labeling to visualize membrane translocation of a myristoyl switch protein.Scientific reports · 2016Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We demonstrate high-density labelling of cellular DNA and RNA using click chemistry and perform confocal and super-resolution microscopy. We visualize the crescent and ring-like structure of densely packed RNA in nucleoli. We further demonstrate click chemistry with unnatural amino acids for super-resolution imaging of outer-membrane proteins of
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.