Evidence map›Paper›PMID 25580090›Full record

ArticleBMC anesthesiology2014

Characteristics, management and outcomes of critically ill patients who are 80 years and older: a retrospective comparative cohort study.

Hasan M Al-Dorzi, Hani M Tamim, Shihab Mundekkadan, Muhammad R Sohail, Yaseen M Arabi

Open access · goldAbstract read
In one paragraph

Article in BMC anesthesiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Article
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  4. Clinical Features and Outcomes of Very Elderly Patients Admitted to the Intensive Care Unit: A Retrospective and Observational Study.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Hasan M Al-DorziCollege of Medicine, King Saud bin Abdulaziz University for Health Sciences and Intensive Care Department, King Abdulaziz Medical City, Riyadh, 11426 Kingdom of Saudi Arabia.
Hani M TamimKing Abdullah International Medical Research Center, Riyadh, 11426 Kingdom of Saudi Arabia ; Department of Internal Medicine, American University of Beirut-Medical Center, Beirut, Lebanon.
Shihab MundekkadanIntensive Care Department, King Abdulaziz Medical City, Riyadh, 11426 Kingdom of Saudi Arabia.
Muhammad R SohailIntensive Care Department, King Abdulaziz Medical City, Riyadh, Saudi Arabia.
Yaseen M ArabiCollege of Medicine, King Saud bin Abdulaziz University for Health Sciences, PO Box 22490, Mail code 1425, Riyadh, 11426 Kingdom of Saudi Arabia.
King Abdulaziz Medical City · SAKing Saud bin Abdulaziz University for Health Sciences · SAKing Abdullah International Medical Research Center · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOlder age is associated with chronic illnesses and disability, which contribute to increased admission to the intensive care unit (ICU). Our primary objective was to compare the characteristics, ICU management and outcomes of critically ill patients ≥ 80 year-old with those of younger patients.

methodsThis was a retrospective cohort study of patients admitted to a tertiary-care ICU from 1999 to 2011. The characteristics, ICU management and outcomes of patients ≥ 80 year-old were compared with those 50-64.9 and 65-79.9 year-old. Multivariate analysis was performed to determine the adjusted risk of Do-Not-Resuscitate orders and hospital mortality in patients ≥ 80 year-old compared with the younger groups.

resultsDuring the study period, patients aged ≥ 80 years (N = 748) represented 7.9% of all ICU admissions and 12.8% of patients aged ≥ 50 years. Chronic cardiac (32.2%) and respiratory (21.8%) diseases were more prevalent in them than the younger groups (p < 0.0001). The most common reasons for their ICU admission were cardiovascular (30.9%) and respiratory (40.4%) conditions. Sepsis was commonly present in them on admission (32.9%). Mechanical ventilation and renal replacement therapy were commonly provided (76.9% and 16.0%, respectively). During ICU stay, Do-Not-Resuscitate orders were more frequently written for patients aged ≥ 80 years (35.0%) compared with 21.9% for 50-64.9 year-old group, p < 0.0001, and 25.4% for the 60-79.9 year-old group, p < 0.0001. On multivariate analysis, patients aged ≥ 80 years were more likely to receive these order compared with the 50-64.9 year-old patients (adjusted OR, 1.83; 95% CI, 1.45-2.31) and the 65-80 year-old patients (adjusted OR, 1.64; 95% CI, 1.32-2.04). The hospital mortality increased gradually with age and was highest (54.6%) in patients ≥ 80 year-old (p < 0.0001). Patients ≥ 80 year-old had higher risk of hospital mortality compared with patients aged 50-64.9 years (adjusted OR, 2.16; 95% CI, 1.73-2.69) and with those aged 65-79.9 years (adjusted OR, 1.51; 95% CI, 1.23-1.86).

conclusionsPatients ≥ 80 year-old represented a significant proportion of ICU admissions. Although they received life sustaining measures similar to younger groups, they had higher adjusted mortality risk compared with the younger groups.

Indexed as

Hospital MortalityAgedAged, 80 and overAge FactorsCohort StudiesCritical CareCritical IllnessFemaleHumansIntensive Care UnitsMaleMiddle AgedMultivariate AnalysisOutcome Assessment, Health CareRespiration, ArtificialResuscitation OrdersAged 80 and overCritical illnessHealth outcomeMortality

Identifiers

PMID25580090
PMCPMC4289550
OpenAlexW1763192599

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.