Evidence map›Paper›PMID 25580086›Full record

SynthesisBMC anesthesiology2014

Transversus abdominis-plane block versus local anesthetic wound infiltration in lower abdominal surgery: a systematic review and meta-analysis of randomized controlled trials.

Nanze Yu, Xiao Long, Jorge R Lujan-Hernandez, Julien Succar, Xin Xin, Xiaojun Wang

4 registry-linked trialsOpen access · goldAbstract readComparative StudyMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in BMC anesthesiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 55 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 4 pooled it
10.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04017013 phase4completednot on this mapstarted 2020, after this paper: background citation

Therapeutic Efficacy of Intravenous Lidocaine Infusion Compared With Epidural Analgesia for Postoperative Pain Control in Adult Patients Undergoing Major Abdominal Surgery: Non-Inferiority Clinical Trial

TypeinterventionalSponsorUniversidad de AntioquiaRan2020 to 2022Enrolled210ConditionsPain, Postoperative, Opioid UseArmsEpidural Analgesia, Lidocaine Infusion
NCT04440475 nacompletednot on this mapstarted 2020, after this paper: background citation

Tap Block vs Conventional Pain Medication for Patients Undergoing Robotic Sacrocolpopexy, a Pilot Study

TypeinterventionalSponsorProMedica Health SystemRan2020 to 2022Enrolled40ConditionsAnesthesia, Local, Prolapse, Prolapse, FemaleArmsTAP block
NCT06220513 nacompletednot on this mapstarted 2024, after this paper: background citation

Ultrasound-guided Erector Spinae Plane Block Versus Transversus Abdominis Plane Block for Postoperative Analgesia of Adult Patients Undergoing Laparoscopic Appendectomy

TypeinterventionalSponsorAin Shams UniversityRan2024 to 2025Enrolled72ConditionsLaparoscopic AppendectomyArmserector spinae plane block (ESP), transversus abdominis plane block(TAP)
NCT06720337 phase4not yet recruitingnot on this mapstarted 2025, after this paper: background citation

Comparative Study Between the Analgesic Effect of Dexmedetomidine and Magnesium Sulfate as Adjuvant to Bupivacaine Using Ultrasound-Guided Transversus Abdominis Plane Block in Abdominal Hysterectomy : A Randomized Double-blinded Study

TypeinterventionalSponsorAssiut UniversityRan2025 to 2026Enrolled64ConditionsHysterectomyArmsbupivacaine 0.5%, Dexmedetomidine, MgSO4
3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 4 syntheses or guidelines pooled it, 142 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Nanze YuDivision of Plastic Surgery, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Science, No.1 Shuaifuyuan, Wangfujing, Dongcheng District, Beijing, 100730 China.
Xiao LongDivision of Plastic Surgery, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Science, No.1 Shuaifuyuan, Wangfujing, Dongcheng District, Beijing, 100730 China.
Jorge R Lujan-HernandezDivision of Plastic Surgery, Brigham and Women's Hospital and Harvard Medical School, Boston, MA USA.
Julien SuccarDepartment of Surgery, University of Kentucky, Lexington, KY USA.
Xin XinDepartment of Anesthesiology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Science, Beijing, China.
Xiaojun WangDivision of Plastic Surgery, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Science, No.1 Shuaifuyuan, Wangfujing, Dongcheng District, Beijing, 100730 China.
Chinese Academy of Medical Sciences & Peking Union Medical College · CNPeking Union Medical College Hospital · CNHarvard University · USUniversity of Kentucky · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPostoperative pain management is of great importance in perioperative anesthetic care. Transversus abdominis plane (TAP) block has been described as an effective technique to reduce postoperative pain and morphine consumption after open lower abdominal operations. Meanwhile, local anesthetic infiltration (LAI) is also commonly used as a traditional method. However, the effectiveness of these two methods has not been compared before.

methodsA meta-analysis of all relevant randomized controlled trials (RCTs) was conducted to compare the efficacy of single shot TAP block with that of single shot LAI for postoperative analgesia in adults. Major medical databases and trial registries were searched for published and unpublished RCTs. The endpoints include postoperative visual analog scale (VAS) pain score, morphine requirement, and rate of postoperative nausea and vomiting (PONV). For continuous data, weighted mean differences (WMDs) were formulated; for dichotomous data, risk ratios (RR) were calculated. Results were derived using a random-/fixed-effects model with 95% confidence interval (CI).

resultsFour RCTs, encompassing 96 TAP-block and 100 LAI patients, were included in the final analysis. Patients in the TAP-block group had lower VAS pain scores 24 hours postoperatively compared with the LAI group, both at rest (WMD [95% CI] = -0.67 [p < 0.01] and with movement (WMD = -0.89, p < 0.01). There were no significant between-group differences in 24-hour postoperative morphine requirements, the rates if PONV or VAS pain scores at 2 and 4 h postoperatively.

conclusionTAP block and LAI provide comparable short-term postoperative analgesia, but TAP block has better long-lasting effect.

Indexed as

AbdomenAdultAnalgesics, OpioidAnesthetics, LocalHumansMorphineNerve BlockPain MeasurementPostoperative Nausea and VomitingPostoperative PainRandomized Controlled Trials as TopicAnalgesics, OpioidAnesthetics, LocalMorphineLocal anesthetic infiltrationMeta-analysisPostoperative analgesiaTransversus abdominis plane block

Identifiers

PMID25580086
PMCPMC4289539
OpenAlexW2135905034

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.