ArticleProceedings of the Indian National Science Academy. Part B, Biological sciences2004
The Eye Specification Network in Drosophila.
Article in Proceedings of the Indian National Science Academy. Part B, Biological sciences, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 10 citations in OpenAlex.
- Article
- Dachshund and C-terminal Binding Protein bind directly duringmicroPublication biology · 2024Article
- Cell types and molecular architecture of the Octopus bimaculoides visual system.Current biology : CB · 2022Article
- Analysis of simple sequence repeats (SSRs)dynamics in fungus Fusarium graminearum.Bioinformation · 2011Article
- Position dependent responses to discontinuities in the retinal determination network.Developmental biology · 2009Article
- Regulation of the retinal determination gene dachshund in the embryonic head and developing eye of Drosophila.Developmental biology · 2006Article
- Persistence time of loss-of-function mutations at nonessential loci affecting eye color in Drosophila melanogaster.Genetics · 2005Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
One of the most exciting revelations in retinal biology is the realization that the molecules and mechanisms that regulate eye development have been conserved in all seeing animals including such diverse organisms as the fruit fly, mouse and man. The emerging commonality among mechanisms used in eye development allows for the use of model systems such as the fruit fly, Drosophila melanogaster, to provide key insights into the development and diseases of the mammalian eye. Eye specification in Drosophila is controlled, in part, by the concerted activities of eight nuclear proteins and several signal transduction cascades that together form a tightly woven regulatory network. Loss of function mutations in several components lead to the complete derailment of eye development while ectopic expression of threse genes in non-retinal tissues can direct the fates of these tissues towards eye formation. Here we will describe what is currently known about this remarkable regulatory cassettee highlight some of the outstanding questions that still need to be answered.
Indexed as
Identifiers
25580038PMC4286332W2398932222What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.