Evidence map›Paper›PMID 25580019›Full record

ArticleThe computer journal2011

NVR-BIP: Nuclear Vector Replacement using Binary Integer Programming for NMR Structure-Based Assignments.

Mehmet Serkan Apaydin, Bülent Çatay, Nicholas Patrick, Bruce R Donald

Abstract read
In one paragraph

Article in The computer journal, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mehmet Serkan ApaydinFaculty of Engineering and Natural Sciences, Sabanci University, Orhanlı Tuzla, 34956 ıstanbul, Turkey.
Bülent ÇatayFaculty of Engineering and Natural Sciences, Sabanci University, Orhanlı Tuzla, 34956 ıstanbul, Turkey.
Nicholas PatrickDepartment of Computer Science, Duke University, Durham, NC 27708, USA.
Bruce R DonaldDepartment of Computer Science, Duke University, Durham, NC 27708, USA ; Department of Biochemistry, Duke University Medical Center, Durham, NC 27708, USA.

Funding

Automated NMR Assignment and Protein Structure DeterminationR01GM065982 · NIGMS · DUKE UNIVERSITY · PI DONALD, BRUCE R. · 2002 to 2011
$2.7M
NIGMS NIH HHS R01 GM065982
6 · The paper itself

Abstract

Nuclear magnetic resonance (NMR) spectroscopy is an important experimental technique that allows one to study protein structure and dynamics in solution. An important bottleneck in NMR protein structure determination is the assignment of NMR peaks to the corresponding nuclei. Structure-based assignment (SBA) aims to solve this problem with the help of a template protein which is homologous to the target and has applications in the study of structure-activity relationship, protein-protein and protein-ligand interactions. We formulate SBA as a linear assignment problem with additional nuclear overhauser effect constraints, which can be solved within nuclear vector replacement's (NVR) framework (Langmead, C., Yan, A., Lilien, R., Wang, L. and Donald, B. (2003) A Polynomial-Time Nuclear Vector Replacement Algorithm for Automated NMR Resonance Assignments.

Indexed as

automated NMR assignmentsbinary integer programmingstructural bioinformatics

Identifiers

PMID25580019
PMCPMC4287374

What OpenQuestion holds

Textmetadata
LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.