Evidence map›Paper›PMID 25578957›Full record

ArticleNature reviews. Microbiology2015

Bacterial morphogenesis and the enigmatic MreB helix.

Jeff Errington

Abstract read
PubMed Publisher
In one paragraph

Article in Nature reviews. Microbiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 77 papers.

0numbers the graph read from it
0cells of the map it votes in
77citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

77 citing papers in PubMed.

  1. Chemical reviews · 2026
    Review
  2. KilR ofmSphere · 2025
    Article
  3. Review
  4. Article
  5. Age-Dependent Pleomorphism inMicroorganisms · 2025
    Article
  6. Article
  7. Improving Stability ofBio-protocol · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. The wall-less bacteriumiScience · 2021
    Article
  20. Article

17 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Jeff ErringtonCentre for Bacterial Cell Biology, Medical Faculty, Newcastle University, Richardson Road, Newcastle-upon-Tyne NE2 4AX, UK.

Funding

Biotechnology and Biological Sciences Research Council BB/G015902/1
6 · The paper itself

Abstract

Work over the past decade has highlighted the pivotal role of the actin-like MreB family of proteins in the determination and maintenance of rod cell shape in bacteria. Early images of MreB localization revealed long helical filaments, which were suggestive of a direct role in governing cell wall architecture. However, several more recent, higher-resolution studies have questioned the existence or importance of the helical structures. In this Opinion article, I navigate a path through these conflicting reports, revive the helix model and summarize the key questions that remain to be answered.

Indexed as

BacteriaBacterial ProteinsCell WallEscherichia coliEscherichia coli ProteinsPeptidoglycanBacterial ProteinsEscherichia coli ProteinsMreB protein, E coliPeptidoglycan

Identifiers

PMID25578957

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.