Evidence map›Paper›PMID 25578632›Full record

ArticleArchives of women's mental health2015

Maladaptive coping mediates the influence of childhood trauma on depression and PTSD among pregnant women in South Africa.

Karmel W Choi, Kathleen J Sikkema, Jennifer Velloza, Adele Marais, Cicyn Jose, Dan J Stein, Melissa H Watt, John A Joska

Open access · greenAbstract read
In one paragraph

Article in Archives of women's mental health, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 5 pooled it
6.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 5 syntheses or guidelines pooled it, 72 citations in OpenAlex.

  1. Pooled it
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  6. Trial
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  8. Trauma as a mediator of childhood adversity and mental illness in South Africa: A path analysis.The South African journal of psychiatry : SAJP : the journal of the Society of Psychiatrists of South Africa · 2025
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  17. Toxic Relationships: The Experiences and Effects of Psychopathy in Romantic Relationships.International journal of offender therapy and comparative criminology · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Karmel W ChoiDepartment of Psychology and Neuroscience, Duke University, Box 90086, Durham, NC, 27708, USA, karmel.choi@duke.edu.
Kathleen J Sikkema
Jennifer Velloza
Adele Marais
Cicyn Jose
Dan J Stein
Melissa H Watt
John A Joska
University of Cape Town · ZADuke Institute for Health Innovation · USDuke University · US

Funding

Social and Behavioral Sciences CoreP30AI064518 · NIAID · DUKE UNIVERSITY · PI Nwora Lance Okeke · 2005 to 2026
$50.5M
Improving the health of South African women with traumatic stress in HIV careR34MH102001 · NIMH · DUKE UNIVERSITY · PI SIKKEMA, KATHLEEN J · 2014 to 2016
$581k
NIAID NIH HHS P30 AI064518NIAID NIH HHS P30-AI064518NIMH NIH HHS R34 MH102001
6 · The paper itself

Abstract

Antenatal mental disorders compromise maternal and child health, and women who have experienced childhood trauma may be at increased risk for such disorders. One hypothesis is that early trauma leads to the development and use of maladaptive coping strategies as an adult, which in turn could predict mental health difficulties during stressful transitions such as pregnancy. To test this hypothesis, this study examined the relationship between childhood trauma and mental health (depression, PTSD) in a sample of 84 pregnant women seeking antenatal care in Cape Town, South Africa, and explored whether maladaptive coping mediated this relationship. The majority of women (62 %) met established criteria for antenatal depression and 30 % for antenatal PTSD; in addition, 40 % reported a history of childhood trauma. Childhood trauma, especially childhood sexual abuse and emotional abuse, was significantly associated with depression and PTSD. The relationships between childhood trauma and depression and PTSD were significantly mediated by maladaptive coping, even when adjusted for the woman's age, gestational age, and HIV status. Findings highlight the need for coping-based interventions to prevent and treat antenatal mental disorders among women with childhood trauma, particularly in high-trauma settings such as South Africa.

Indexed as

Adaptation, PsychologicalAdolescentAdultChildChild Abuse, SexualDepressionFemaleHumansPregnancyPregnant PeopleRetrospective StudiesSouth AfricaStress Disorders, Post-TraumaticSuburban PopulationSurveys and Questionnaires

Identifiers

PMID25578632
PMCPMC4500677
OpenAlexW2040363563

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.