ArticleHistochemistry and cell biology2015
Spatiotemporal expression of Math6 during mouse embryonic development.
Article in Histochemistry and cell biology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Role of ATOH8 in Mitigating Cardiac Fibrosis in Heart Failure via Inhibition of the Transcriptional Repression of Smad7 by RUNX2.Biomolecules & therapeutics · 2026Article
- The Effects of Atoh8 on Postnatal Murine Neurogenesis.Cells, tissues, organs · 2025Article
- Article
- miScience · 2022Article
- Atoh8 in Development and Disease.Biology · 2022Review
- Mitochondria dysfunction in circulating tumor cells.Frontiers in oncology · 2022Review
- Targeted deletion of Atoh8 results in severe hearing loss in mice.Genesis (New York, N.Y. : 2000) · 2021Article
- Shear stress activates ATOH8 via autocrine VEGF promoting glycolysis dependent-survival of colorectal cancer cells in the circulation.Journal of experimental & clinical cancer research : CR · 2020Article
- BMP-induced Atoh8 attenuates osteoclastogenesis by suppressing Runx2 transcriptional activity and reducing the Rankl/Opg expression ratio in osteoblasts.Bone research · 2020Article
- Genome-wide association study of circulating folate one-carbon metabolites.Genetic epidemiology · 2019Article
- Article
- Atoh8 acts as a regulator of chondrocyte proliferation and differentiation in endochondral bones.PloS one · 2019Article
- Murine transcription factor Math6 is a regulator of placenta development.Scientific reports · 2018Article
- The Histochemistry and Cell Biology omnium-gatherum: the year 2015 in review.Histochemistry and cell biology · 2016Review
- A novel interaction between ATOH8 and PPP3CB.Histochemistry and cell biology · 2016Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The basic helix-loop-helix transcription factor Math6 was shown to have important regulatory functions during many developmental events. However, a systematic description of Math6 expression during mouse embryonic development is up to now still lacking. We carried out this study to show Math6 expression at different stages of mouse embryonic development aiming to provide a wide insight into the regulatory functions during the mouse organogenesis. Using immunohistochemistry, we could show that Math6 expression is activated in the inner cell mass at the blastocyst stage and in the neural tube as well as somatic and splanchnic mesoderm at stage E8.5. At stages E8.5 and E10.5, Math6 transcripts were detected in the myotome, neural tube, pharyngeal arches, foregut and heart. At stages E11.5 and E12.5, Math6 transcripts were accumulated in the developing brain, heart, limb buds and liver. The heterozygous transgenic mouse embryos carrying EGFP-Cre under the Math6 promoter were used to analyze Math6 expression at later stages by means of immunohistochemistry against EGFP protein. EGFP was observed in the neural tube, heart, lung, skeletal muscle, skin, cartilage, trachea and aorta. We have observed Math6 expression in various organs at early and late stages of mouse development, which illustrates the involvement of Math6 in multiple developmental events.
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Registered trials
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