ArticleThe Journal of allergy and clinical immunology2015
Influence of childhood growth on asthma and lung function in adolescence.
Article in The Journal of allergy and clinical immunology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 60 citations in OpenAlex.
- A Health-Literacy Intervention for Early Childhood Obesity Prevention: A Cluster-Randomized Controlled Trial.Pediatrics · 2021Trial
- Bottle Size and Weight Gain in Formula-Fed Infants.Pediatrics · 2016Trial
- Obesity-Related Asthma: Structure and Inflammation.Current allergy and asthma reports · 2026Review
- Association of childhood growth with adult lung function: A prospective urban birth cohort study from India.The Indian journal of medical research · 2026Article
- Combining bioinformatics and machine learning to identify common mechanisms and biomarkers of childhood asthma and obesity.Translational pediatrics · 2026Article
- Body mass index, lung function, and FeNO in children with positive bronchodilator response: a cross-sectional study.Frontiers in pediatrics · 2026Article
- Body mass index trajectories from birth to early adulthood and lung function development.The European respiratory journal · 2025Article
- Body mass index trajectories may represent modifiable targets in the promotion of respiratory health.The European respiratory journal · 2025Article
- A clinician's guide to effects of obesity on childhood asthma and into adulthood.Expert review of respiratory medicine · 2024Review
- Association between Childhood Asthma Control Test scores and lung pathophysiologic indicators in longitudinal measurements.Journal of thoracic disease · 2023Article
- Early Origins of Chronic Obstructive Pulmonary Disease: Prenatal and Early Life Risk Factors.International journal of environmental research and public health · 2023Review
- Obesity-related asthma in children and adolescents.The Lancet. Child & adolescent health · 2022Review
- Spirometric phenotypes from early childhood to young adulthood: a Chronic Airway Disease Early Stratification study.ERJ open research · 2021Article
- Pre-adolescence DNA methylation is associated with lung function trajectories from pre-adolescence to adulthood.Clinical epigenetics · 2021Article
- Changes of DNA methylation are associated with changes in lung function during adolescence.Respiratory research · 2020Article
- Pediatric obesity-related asthma: A prototype of pediatric severe non-T2 asthma.Pediatric pulmonology · 2020Article
- Association of pediatric obesity and asthma, pulmonary physiology, metabolic dysregulation, and atopy; and the role of weight management.Expert review of endocrinology & metabolism · 2019Review
- Distinctive lung function trajectories from age 10 to 26 years in men and women and associated early life risk factors - a birth cohort study.Respiratory research · 2019Article
- Key paediatric messages from the 2018 European Respiratory Society International Congress.ERJ open research · 2019Article
- Introduction of fish and other foods during infancy and risk of asthma in the All Babies In Southeast Sweden cohort study.European journal of pediatrics · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundLow birth weight and rapid infant growth in early infancy are associated with increased risk of childhood asthma, but little is known about the role of postinfancy growth in asthmatic children.
objectivesWe sought to examine the associations of children's growth patterns with asthma, bronchial responsiveness, and lung function until adolescence.
methodsIndividual growth trajectories from birth until 10 years of age were estimated by using linear spline multilevel models for 9723 children participating in a population-based prospective cohort study. Current asthma at 8, 14, and 17 years of age was based on questionnaires. Lung function and bronchial responsiveness or reversibility were measured during clinic visits at 8 and 15 years of age.
resultsRapid weight growth between 0 and 3 months of age was most consistently associated with increased risks of current asthma at the ages of 8 and 17 years, bronchial responsiveness at age 8 years, and bronchial reversibility at age 15 years. Rapid weight growth was associated with lung function values, with the strongest associations for weight gain between 3 and 7 years of age and higher forced vital capacity (FVC) and FEV1 values at age 15 years (0.12 [95% CI, 0.08 to 0.17] and 0.11 [95% CI, 0.07 to 0.15], z score per SD, respectively) and weight growth between 0 and 3 months of age and lower FEV1/FVC ratios at age 8 and 15 years (-0.13 [95% CI, -0.16 to -0.10] and -0.04 [95% CI, -0.07 to -0.01], z score per SD, respectively). Rapid length growth was associated with lower FVC and FVC1 values at age 15 years.
conclusionFaster weight growth in early childhood is associated with asthma and bronchial hyperresponsiveness, and faster weight growth across childhood is associated with higher FVC and FEV1 values.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.