ArticleApplied and environmental microbiology2015
Arsenite oxidase also functions as an antimonite oxidase.
Article in Applied and environmental microbiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed.
- Arsenic biosorption mediated by arsenic-binding proteins QueF and QueE inApplied and environmental microbiology · 2025Article
- Genome Deletions and Rewiring of the Transcriptome Underlying High Antimonite Resistance inInternational journal of molecular sciences · 2024Article
- Antimony resistant bacteria isolated from Budúcnosť adit (Pezinok-Kolársky vrch deposit) in western Slovakia.Heliyon · 2024Article
- Responses of biomarkers, joint effect and drilosphere bacterial communities to antimony (III and/or V) contamination.Heliyon · 2024Article
- Isolation and Identification of Highly Sb-Resistant Rhodotorula glutinis Strain J5 and its Mechanism of Resistance to Sb(III).Current microbiology · 2024Review
- Identification of bacterial dissimilatory antimonate reductase AnrA: genes and proteins involved in antimonate respiration and resistance inApplied and environmental microbiology · 2024Article
- Nitrate-dependent antimony oxidase in an uncultured Symbiobacteriaceae member.The ISME journal · 2024Article
- Widespread Distribution of theEnvironmental science & technology · 2023Article
- Desulfurivibrio spp. mediate sulfur-oxidation coupled to Sb(V) reduction, a novel biogeochemical process.The ISME journal · 2022Article
- Oxidation of organoarsenicals and antimonite by a novel flavin monooxygenase widely present in soil bacteria.Environmental microbiology · 2022Article
- Nanozymes-Hitting the Biosensing "Target".Sensors (Basel, Switzerland) · 2021Review
- A Critical Review of Resistance and Oxidation Mechanisms of Sb-Oxidizing Bacteria for the Bioremediation of Sb(III) Pollution.Frontiers in microbiology · 2021Review
- Integrated Metabolomics and Targeted Gene Transcription Analysis Reveal Global Bacterial Antimonite Resistance Mechanisms.Frontiers in microbiology · 2021Article
- A Sensitive Magnetic Arsenite-Specific Biosensor Hosted in Magnetotactic Bacteria.Applied and environmental microbiology · 2020Article
- Functional mononuclear molybdenum enzymes: challenges and triumphs in molecular cloning, expression, and isolation.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2020Review
- Complete genome sequencing and comparative genomic analyses of Bacillus sp. S3, a novel hyper Sb(III)-oxidizing bacterium.BMC microbiology · 2020Article
- Microbial Oxidation of Arsenite: Regulation, Chemotaxis, Phosphate Metabolism and Energy Generation.Frontiers in microbiology · 2020Review
- Impacts of Arsenic and Antimony Co-Contamination on Sedimentary Microbial Communities in Rivers with Different Pollution Gradients.Microbial ecology · 2019Article
- Efflux proteins MacAB confer resistance to arsenite and penicillin/macrolide-type antibiotics in Agrobacterium tumefaciens 5A.World journal of microbiology & biotechnology · 2019Article
- Anaerobic Bacterial Immobilization and Removal of Toxic Sb(III) Coupled With Fe(II)/Sb(III) Oxidation and Denitrification.Frontiers in microbiology · 2019Article
Corrections and comments
- Erratum issued
Authors and funding
10 authors.
Funding
Abstract
Arsenic and antimony are toxic metalloids and are considered priority environmental pollutants by the U.S. Environmental Protection Agency. Significant advances have been made in understanding microbe-arsenic interactions and how they influence arsenic redox speciation in the environment. However, even the most basic features of how and why a microorganism detects and reacts to antimony remain poorly understood. Previous work with Agrobacterium tumefaciens strain 5A concluded that oxidation of antimonite [Sb(III)] and arsenite [As(III)] required different biochemical pathways. Here, we show with in vivo experiments that a mutation in aioA [encoding the large subunit of As(III) oxidase] reduces the ability to oxidize Sb(III) by approximately one-third relative to the ability of the wild type. Further, in vitro studies with the purified As(III) oxidase from Rhizobium sp. strain NT-26 (AioA shares 94% amino acid sequence identity with AioA of A. tumefaciens) provide direct evidence of Sb(III) oxidation but also show a significantly decreased Vmax compared to that of As(III) oxidation. The aioBA genes encoding As(III) oxidase are induced by As(III) but not by Sb(III), whereas arsR gene expression is induced by both As(III) and Sb(III), suggesting that detection and transcriptional responses for As(III) and Sb(III) differ. While Sb(III) and As(III) are similar with respect to cellular extrusion (ArsB or Acr3) and interaction with ArsR, they differ in the regulatory mechanisms that control the expression of genes encoding the different Ars or Aio activities. In summary, this study documents an enzymatic basis for microbial Sb(III) oxidation, although additional Sb(III) oxidation activity also is apparent in this bacterium.
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