ArticleProceedings of the National Academy of Sciences of the United States of America2015
Identifying strains that contribute to complex diseases through the study of microbial inheritance.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
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Who cites it
37 citing papers in PubMed.
- Article
- A data-driven universal gut microbiome health assessment: a machine learning framework trained on large metagenomic data.Frontiers in microbiology · 2026Article
- Assessing live microbial therapeutic transmission.Gut microbes · 2025Review
- Adaptive Evolution in the Mammalian Gut Microbiota: Insights and Discoveries.Current microbiology · 2025Review
- Straining to define a healthy microbiome.mSphere · 2025Review
- Article
- Antimicrobial Resistance in the Global Health Network: Known Unknowns and Challenges for Efficient Responses in the 21st Century.Microorganisms · 2023Review
- Staphylococcal diversity in atopic dermatitis from an individual to a global scale.Cell host & microbe · 2023Article
- Immunoglobulin A antibody composition is sculpted to bind the self gut microbiome.Science immunology · 2022Article
- Article
- Precise quantification of bacterial strains after fecal microbiota transplantation delineates long-term engraftment and explains outcomes.Nature microbiology · 2021Article
- Host adaptation in gut Firmicutes is associated with sporulation loss and altered transmission cycle.Genome biology · 2021Article
- Role of Gut Microbiota in the Skeletal Response to PTH.The Journal of clinical endocrinology and metabolism · 2021Review
- Article
- A predictive index for health status using species-level gut microbiome profiling.Nature communications · 2020Article
- Diet-microbiome-disease: Investigating diet's influence on infectious disease resistance through alteration of the gut microbiome.PLoS pathogens · 2019Review
- Understanding the Role of the Gut Microbiome and Microbial Metabolites in Obesity and Obesity-Associated Metabolic Disorders: Current Evidence and Perspectives.Current obesity reports · 2019Review
- Simulating Multilevel Dynamics of Antimicrobial Resistance in a Membrane Computing Model.mBio · 2019Article
- Gut and Lung Microbiota in Preterm Infants: Immunological Modulation and Implication in Neonatal Outcomes.Frontiers in immunology · 2019Review
- Review
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
It has been 35 y since Carl Woese reported in PNAS how sequencing ribosomal RNA genes could be used to distinguish the three domains of life on Earth. During the past decade, 16S rDNA sequencing has enabled the now frequent enumeration of bacterial communities that populate the bodies of humans representing different ages, cultural traditions, and health states. A challenge going forward is to quantify the contributions of community members to wellness, disease risk, and disease pathogenesis. Here, we explore a theoretical framework for studies of the inheritance of bacterial strains and discuss the advantages and disadvantages of various study designs for assessing the contribution of strains to complex diseases.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.