Trial reportEuropean journal of applied physiology2015
Non-invasive estimation of hydration status changes through tear fluid osmolarity during exercise and post-exercise rehydration.
Trial report in European journal of applied physiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed.
- Wireless Soft Athlete Bioelectronics for Monitoring Carbon Dioxide Ventilation and Physiological Performance.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Sweat, tears, and beyond: advanced wearable sensors for personalized health and athletic performance.Frontiers in bioengineering and biotechnology · 2025Review
- A Review on In Vivo Research Dehydration Models and Application of Rehydration Strategies.Nutrients · 2024Review
- Explaining variation in sweat sodium concentration: effect of individual characteristics and exercise, environmental, and dietary factors.Journal of applied physiology (Bethesda, Md. : 1985) · 2022Article
- Relationship Between Pre- and Post-exercise Body Mass Changes and Pre-exercise Urine Color in Female Athletes.Frontiers in sports and active living · 2022Article
- Molecular and physical technologies for monitoring fluid and electrolyte imbalance: A focus on cancer population.Clinical and translational medicine · 2021Review
- Tear Osmolarity in the Diagnosis of Systemic Dehydration and Dry Eye Disease.Diagnostics (Basel, Switzerland) · 2021Review
- Fluorescent contact lens for continuous non-invasive measurements of sodium and chloride ion concentrations in tears.Analytical biochemistry · 2020Article
- Reviewing the current methods of assessing hydration in athletes.Journal of the International Society of Sports Nutrition · 2020Review
- Does Oxygen Uptake Before Physical Exercise Affect Tear Osmolarity?Journal of human kinetics · 2020Article
- Hydration Status and Fluid Needs of Division I Female Collegiate Athletes Exercising Indoors and Outdoors.Sports (Basel, Switzerland) · 2019Article
- Alteration of Blinking and Sex Differences During Physical Exercise Affect Tear Osmolarity.Journal of human kinetics · 2019Article
- The correlation between plasma osmolarity and tear osmolarity.International ophthalmology · 2018Article
- Evaluation and review of body fluids saliva, sweat and tear compared to biochemical hydration assessment markers within blood and urine.European journal of clinical nutrition · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo determine if tear fluid osmolarity (Tosm) can track changes in hydration status during exercise and post-exercise rehydration.
methodsNineteen male athletes (18-37 years, 74.6 ± 7.9 kg) completed two randomized, counterbalanced trials; cycling (~95 min) with water intake to replace fluid losses or water restriction to progressively dehydrate to 3 % body mass loss (BML). After exercise, subjects drank water to maintain body mass (water intake trials) or progressively rehydrate to pre-exercise body mass (water restriction trials) over a 90-min recovery period. Plasma osmolality (Posm) and Tosm measurements (mean of right and left eyes) were taken pre-exercise, during rest periods between exercise bouts corresponding to 1, 2, and 3 % BML, and rehydration at 2, 1, and 0 % BML.
resultsDuring exercise mean (± SD) Tosm was significantly higher in water restriction vs. water intake trials at 1 % BML (299 ± 9 vs. 293 ± 9 mmol/L), 2 % BML (301 ± 9 vs. 294 ± 9 mmol/L), and 3 % BML (302 ± 9 vs. 292 ± 8 mmol/L). Mean Tosm progressively decreased during post-exercise rehydration and was not different between trials at 1 % BML (291 ± 8 vs. 290 ± 7 mmol/L) and 0 % BML (288 ± 7 vs. 289 ± 8 mmol/L). Mean Tosm tracked changes in hydration status similar to that of mean Posm; however, the individual responses in Tosm to water restriction and water intake was considerably more variable than that of Posm.
conclusionTosm is a valid indicator of changes in hydration status when looking at the group mean; however, large differences among subjects in the Tosm response to hydration changes limit its validity for individual recommendations.
Indexed as
Identifiers
25576262What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.