ArticleDer Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete2015
[Abscopal effect in the treatment of malignant melanoma].
Article in Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed, 19 citations in OpenAlex.
- Abscopal Effect in Metastatic Melanoma: Generating Clinical Insights From Radiation-Induced Immune Response.Cureus · 2024Review
- Abscopal Effects in Metastatic Cancer: Is a Predictive Approach Possible to Improve Individual Outcomes?Journal of clinical medicine · 2021Review
- Immunostimulatory Effects of Radiotherapy for Local and Systemic Control of Melanoma: A Review.International journal of molecular sciences · 2020Review
- Extracranial abscopal effect induced by combining immunotherapy with brain radiotherapy in a patient with lung adenocarcinoma: A case report and literature review.Thoracic cancer · 2019Review
- Review
- Time to abandon single-site irradiation for inducing abscopal effects.Nature reviews. Clinical oncology · 2019Review
- Review of cancer treatment with immune checkpoint inhibitors : Current concepts, expectations, limitations and pitfalls.Wiener klinische Wochenschrift · 2018Review
- Immune checkpoint blockade with concurrent electrochemotherapy in advanced melanoma: a retrospective multicenter analysis.Cancer immunology, immunotherapy : CII · 2016Article
- Stereotactic Ablative Radiation Therapy Combined With Immunotherapy for Solid Tumors.Cancer journal (Sudbury, Mass.)Review
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe clearance of non-irradiated tumors after localized radiation therapy is known as the abscopal effect. CASE REPORT: In the present case report we initiated a combined therapeutic approach based on sequential administration of ipilimumab plus temozolomide in combination with radiotherapy. The treatment regime was well tolerated and resulted in unusually long disease stabilization and in a complete response of brain and kidney metastases. Thus, it is speculated that the clinical response was the result of an abscopal effect.
conclusionThe present case report highlights the possible clinical benefit of the abscopal effect in the treatment of malignant melanoma.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.